| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | a-1,2,3,4,5,6-hexachlorocyclohexane 10.1 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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69 genes differentially expressed following the CRCGN012_HEPG2_24H:K15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.67656 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.16088 |
| STIMATE | STIM activating enhancer | 5.11582 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 5.07313 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.13184 |
| SMIM40 | small integral membrane protein 40 | 4.01096 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.88779 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.83758 |
| UBQLN2 | ubiquilin 2 | 3.80824 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 3.74153 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 3.72392 |
| LCN2 | lipocalin 2 | 3.63981 |
| TBP | TATA box binding protein | 3.45668 |
| KLHL9 | kelch-like family member 9 | 3.22629 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.05752 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.99316 |
| KIF5C | kinesin family member 5C | 2.91352 |
| FPGS | folylpolyglutamate synthase | 2.71376 |
| VGLL4 | vestigial-like family member 4 | 2.64399 |
| GATA3 | GATA binding protein 3 | 2.57631 |
| CHN1 | chimerin 1 | 2.54775 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 | 2.53715 |
| CCNA1 | cyclin A1 | 2.3838 |
| OBI1 | ORC ubiquitin ligase 1 | 2.31276 |
| CCDC85B | coiled-coil domain containing 85B | 2.30587 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 2.30053 |
| PAQR3 | progestin and adipoQ receptor family member III | 2.24998 |
| SCARA3 | scavenger receptor class A, member 3 | 2.22468 |
| TEFM | transcription elongation factor, mitochondrial | 2.18955 |
| CYCS | cytochrome c, somatic | 2.14536 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 2.12334 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNM1L | dynamin 1-like | -9.18979 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -8.57978 |
| CCNB2 | cyclin B2 | -8.03723 |
| GDF15 | growth differentiation factor 15 | -7.62136 |
| NGRN | neugrin, neurite outgrowth associated | -5.67894 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.1117 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.03892 |
| HSPB1 | heat shock 27kDa protein 1 | -4.73361 |
| GNAS | GNAS complex locus | -4.61014 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.27023 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.23567 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -4.014 |
| CCNB1 | cyclin B1 | -3.8485 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.42243 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.35448 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | -3.17094 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.08591 |
| PCNA | proliferating cell nuclear antigen | -2.80112 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.58689 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.56011 |
| NSMAF | neutral sphingomyelinase (N-SMase) activation associated factor | -2.31811 |
| TTC17 | tetratricopeptide repeat domain 17 | -2.30924 |
| NDUFB1 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | -2.303 |
| B2M | beta-2-microglobulin | -2.29815 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -2.25925 |
| EGF | epidermal growth factor | -2.24231 |
| SNRPE | small nuclear ribonucleoprotein polypeptide E | -2.18796 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -2.18453 |
| LILRA4 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 | -2.17761 |
| FGF18 | fibroblast growth factor 18 | -2.14506 |
| EPHA5 | EPH receptor A5 | -2.08882 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -2.08094 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -2.06711 |
| PDHX | pyruvate dehydrogenase complex, component X | -2.04454 |
| USP6 | ubiquitin specific peptidase 6 | -2.04299 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | -2.04298 |
| FKBP3 | FK506 binding protein 3, 25kDa | -2.01246 |
| TNMD | tenomodulin | -2.00541 |
