CRCGN012_HEPG2_24H:K19 Gene Set
Genes
52 genes differentially expressed following the CRCGN012_HEPG2_24H:K19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
7.00907
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
6.91483
|
|
EPHA3
|
EPH receptor A3
|
4.16438
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.83624
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.78704
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.77306
|
|
PRR15L
|
proline rich 15-like
|
3.58737
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.54866
|
|
LCN2
|
lipocalin 2
|
3.15938
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.1499
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.05745
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.94024
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.90221
|
|
STIMATE
|
STIM activating enhancer
|
2.88572
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.81333
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.79768
|
|
PRKCD
|
protein kinase C, delta
|
2.74178
|
|
CTSL
|
cathepsin L
|
2.7412
|
|
E2F2
|
E2F transcription factor 2
|
2.58588
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.53699
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
2.50981
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.50348
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.45749
|
|
CHN1
|
chimerin 1
|
2.262
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.01733
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.67203
|
|
CCNB2
|
cyclin B2
|
-5.19309
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-5.04605
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-4.20063
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-4.01801
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-3.94648
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.6166
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.60436
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.39689
|
|
VAT1
|
vesicle amine transport 1
|
-3.23617
|
|
SNX11
|
sorting nexin 11
|
-3.21457
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.18017
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.16646
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.9723
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.96752
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.95432
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.87118
|
|
SMC6
|
structural maintenance of chromosomes 6
|
-2.45638
|
|
ARFIP2
|
ADP-ribosylation factor interacting protein 2
|
-2.44241
|
|
RRAS2
|
related RAS viral (r-ras) oncogene homolog 2
|
-2.30205
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.21792
|
|
SCG2
|
secretogranin II
|
-2.20175
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.18351
|
|
MTFR1
|
mitochondrial fission regulator 1
|
-2.18129
|
|
LAPTM5
|
lysosomal protein transmembrane 5
|
-2.11804
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.04696
|
|
NSMAF
|
neutral sphingomyelinase (N-SMase) activation associated factor
|
-2.01756
|
