CRCGN012_HEPG2_24H:K20 Gene Set
Genes
51 genes differentially expressed following the CRCGN012_HEPG2_24H:K20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.6348
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.25491
|
|
NOTCH1
|
notch 1
|
3.97048
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.9364
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.85205
|
|
FPGS
|
folylpolyglutamate synthase
|
3.55229
|
|
SLC75A1
|
solute carrier family 75 member 1
|
3.27746
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.24694
|
|
CCNH
|
cyclin H
|
3.0008
|
|
CHN1
|
chimerin 1
|
2.90099
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.84726
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.79041
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.77773
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.62812
|
|
EVL
|
Enah/Vasp-like
|
2.6024
|
|
CCNF
|
cyclin F
|
2.57485
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.55425
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.53175
|
|
GPATCH8
|
G patch domain containing 8
|
2.42566
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.32883
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.22384
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
2.2083
|
|
HEBP1
|
heme binding protein 1
|
2.06628
|
|
RRAGA
|
Ras-related GTP binding A
|
2.02991
|
|
TBP
|
TATA box binding protein
|
2.00353
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-8.38473
|
|
VAT1
|
vesicle amine transport 1
|
-7.39046
|
|
USP6NL
|
USP6 N-terminal like
|
-4.41689
|
|
TUBB6
|
tubulin, beta 6 class V
|
-4.02777
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-3.95873
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-3.84829
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.43023
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.2049
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-3.20174
|
|
LDHD
|
lactate dehydrogenase D
|
-3.10917
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.03172
|
|
HMG20B
|
high mobility group 20B
|
-2.9754
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.92698
|
|
TES
|
testin LIM domain protein
|
-2.92456
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.7872
|
|
THAP11
|
THAP domain containing 11
|
-2.49974
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.49501
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.4876
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.40421
|
|
GDF15
|
growth differentiation factor 15
|
-2.2684
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.25016
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.19648
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.15014
|
|
GRB7
|
growth factor receptor-bound protein 7
|
-2.05378
|
|
SFT2D2
|
SFT2 domain containing 2
|
-2.04907
|
|
ZW10
|
zw10 kinetochore protein
|
-2.02245
|
