CRCGN012_HEPG2_24H:K21 Gene Set
Genes
36 genes differentially expressed following the CRCGN012_HEPG2_24H:K21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
8.50665
|
|
PRR15L
|
proline rich 15-like
|
5.55564
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.73689
|
|
MYLK
|
myosin light chain kinase
|
4.46779
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.41478
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
4.03846
|
|
CBR3
|
carbonyl reductase 3
|
3.39121
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.31881
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.83635
|
|
H2BC12
|
H2B clustered histone 12
|
2.73408
|
|
EVL
|
Enah/Vasp-like
|
2.65219
|
|
UBE2A
|
ubiquitin-conjugating enzyme E2A
|
2.505
|
|
STX1A
|
syntaxin 1A (brain)
|
2.35079
|
|
WDR7
|
WD repeat domain 7
|
2.27286
|
|
HEBP1
|
heme binding protein 1
|
2.26764
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
2.26736
|
|
SIRT3
|
sirtuin 3
|
2.11363
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.11002
|
|
APOL3
|
apolipoprotein L, 3
|
2.06221
|
|
TERF2
|
telomeric repeat binding factor 2
|
2.03173
|
|
S1PR4
|
sphingosine-1-phosphate receptor 4
|
2.01511
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-5.4719
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.37354
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.18669
|
|
VAT1
|
vesicle amine transport 1
|
-3.74954
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-3.44756
|
|
SNX11
|
sorting nexin 11
|
-3.12766
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.96454
|
|
PDLIM1
|
PDZ and LIM domain 1
|
-2.83043
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.42951
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.35091
|
|
RNF167
|
ring finger protein 167
|
-2.33585
|
|
GRAMD4
|
GRAM domain containing 4
|
-2.29128
|
|
PDCL3
|
phosducin-like 3
|
-2.04014
|
|
WDR11
|
WD repeat domain 11
|
-2.01121
|
|
CUTA
|
cutA divalent cation tolerance homolog (E. coli)
|
-2.00151
|
