CRCGN012_HEPG2_24H:K24 Gene Set
Genes
48 genes differentially expressed following the CRCGN012_HEPG2_24H:K24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
KLHL21
|
kelch-like family member 21
|
4.99299
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.43682
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
4.09657
|
|
CSK
|
c-src tyrosine kinase
|
4.05256
|
|
CBR3
|
carbonyl reductase 3
|
3.91621
|
|
CHN1
|
chimerin 1
|
3.91266
|
|
MYLK
|
myosin light chain kinase
|
3.51024
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.33913
|
|
RRAGA
|
Ras-related GTP binding A
|
3.28864
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.1634
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.11695
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.11424
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
3.07236
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.85915
|
|
JADE2
|
jade family PHD finger 2
|
2.84609
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.7357
|
|
UBQLN2
|
ubiquilin 2
|
2.63271
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.6245
|
|
KAT6A
|
K(lysine) acetyltransferase 6A
|
2.44086
|
|
CDK6
|
cyclin-dependent kinase 6
|
2.29626
|
|
NOTCH1
|
notch 1
|
2.23653
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.13707
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.09633
|
|
MBNL1
|
muscleblind-like splicing regulator 1
|
2.08292
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GDF15
|
growth differentiation factor 15
|
-5.76642
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-4.1143
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.96644
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.66382
|
|
COG7
|
component of oligomeric golgi complex 7
|
-3.54124
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.24165
|
|
GNAS
|
GNAS complex locus
|
-3.22174
|
|
ZW10
|
zw10 kinetochore protein
|
-3.13291
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.02
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.83686
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.77324
|
|
CD58
|
CD58 molecule
|
-2.55073
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.52919
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.4761
|
|
HMG20B
|
high mobility group 20B
|
-2.47223
|
|
LDHD
|
lactate dehydrogenase D
|
-2.45561
|
|
CCNB1
|
cyclin B1
|
-2.40743
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.38324
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.36015
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.28864
|
|
CANT1
|
calcium activated nucleotidase 1
|
-2.22688
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.11642
|
|
BUB1B
|
BUB1 mitotic checkpoint serine/threonine kinase B
|
-2.07967
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.0552
|
