CRCGN012_HEPG2_24H:L08 Gene Set
Genes
36 genes differentially expressed following the CRCGN012_HEPG2_24H:L08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
4.22648
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.79645
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.76923
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.03899
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.92493
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.91569
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.86598
|
|
EPHB2
|
EPH receptor B2
|
2.74411
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.68251
|
|
EPN2
|
epsin 2
|
2.63179
|
|
E2F2
|
E2F transcription factor 2
|
2.52376
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
2.48262
|
|
MYLK
|
myosin light chain kinase
|
2.46557
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.29535
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.23324
|
|
CSK
|
c-src tyrosine kinase
|
2.07791
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.07466
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.03638
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
FASTKD5
|
FAST kinase domains 5
|
-5.08036
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.23935
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.06894
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.92645
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-3.48427
|
|
ZNF586
|
zinc finger protein 586
|
-3.3901
|
|
GNAS
|
GNAS complex locus
|
-3.13655
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.12059
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.97366
|
|
RPIA
|
ribose 5-phosphate isomerase A
|
-2.91385
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.70357
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.58155
|
|
PDLIM1
|
PDZ and LIM domain 1
|
-2.58142
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.48057
|
|
GDF15
|
growth differentiation factor 15
|
-2.34527
|
|
TCTN1
|
tectonic family member 1
|
-2.24582
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.11383
|
|
HMBOX1
|
homeobox containing 1
|
-2.09333
|
