| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tryptophan 10.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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57 genes differentially expressed following the CRCGN012_HEPG2_24H:L09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 8.93861 |
| PLSCR1 | phospholipid scramblase 1 | 6.36338 |
| UBQLN2 | ubiquilin 2 | 5.21619 |
| SMIM40 | small integral membrane protein 40 | 4.93903 |
| LCN2 | lipocalin 2 | 4.59918 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.56493 |
| CCDC85B | coiled-coil domain containing 85B | 4.47323 |
| FZD7 | frizzled class receptor 7 | 4.29541 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.27923 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.09693 |
| CHMP6 | charged multivesicular body protein 6 | 4.07948 |
| SQOR | sulfide quinone oxidoreductase | 3.93859 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 3.62364 |
| CSK | c-src tyrosine kinase | 3.53367 |
| NOTCH1 | notch 1 | 3.36367 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.27675 |
| CYCS | cytochrome c, somatic | 3.25097 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.09556 |
| ABHD6 | abhydrolase domain containing 6 | 3.06671 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.99906 |
| VGLL4 | vestigial-like family member 4 | 2.73711 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 2.54776 |
| LOC122526780 | uncharacterized LOC122526780 | 2.36537 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.35525 |
| CCNF | cyclin F | 2.34044 |
| NMU | neuromedin U | 2.30622 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | 2.29448 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.24688 |
| BLVRB | biliverdin reductase B | 2.09738 |
| JPT1 | Jupiter microtubule associated homolog 1 | 2.05267 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAPK13 | mitogen-activated protein kinase 13 | -6.47598 |
| TUBB6 | tubulin, beta 6 class V | -4.98012 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -4.78404 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.41033 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.27955 |
| MAP7 | microtubule-associated protein 7 | -4.20411 |
| CHMP4B | charged multivesicular body protein 4B | -4.11294 |
| BLCAP | bladder cancer associated protein | -4.08222 |
| NVL | nuclear VCP-like | -3.9932 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -3.97875 |
| GNAS | GNAS complex locus | -3.95964 |
| LDHD | lactate dehydrogenase D | -3.80369 |
| YME1L1 | YME1-like 1 ATPase | -3.36665 |
| ANKRD10 | ankyrin repeat domain 10 | -3.33183 |
| CCNB2 | cyclin B2 | -3.27684 |
| ZNF586 | zinc finger protein 586 | -3.19563 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -3.1144 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.91053 |
| PEG10 | paternally expressed 10 | -2.73278 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.63824 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.36133 |
| AFF4 | AF4/FMR2 family, member 4 | -2.35552 |
| CCNB1 | cyclin B1 | -2.25239 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | -2.21718 |
| PDHX | pyruvate dehydrogenase complex, component X | -2.20682 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 | -2.03779 |
| MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | -2.03061 |
