| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tryptophan 2.5 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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60 genes differentially expressed following the CRCGN012_HEPG2_24H:L11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 6.063 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 5.54484 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.1008 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.94702 |
| KLHL21 | kelch-like family member 21 | 4.90119 |
| CHMP6 | charged multivesicular body protein 6 | 4.88702 |
| CHN1 | chimerin 1 | 4.84635 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.76965 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.42248 |
| MAMLD1 | mastermind-like domain containing 1 | 4.35974 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 3.69998 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 3.65844 |
| EPHA3 | EPH receptor A3 | 3.63741 |
| STIMATE | STIM activating enhancer | 3.62499 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.52827 |
| E2F2 | E2F transcription factor 2 | 3.32296 |
| RPL39L | ribosomal protein L39-like | 3.072 |
| LCN2 | lipocalin 2 | 3.01234 |
| CSK | c-src tyrosine kinase | 3.00365 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.99908 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.98854 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 2.78057 |
| NMU | neuromedin U | 2.61766 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 2.60086 |
| NOSIP | nitric oxide synthase interacting protein | 2.46636 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 2.40696 |
| PCNA | proliferating cell nuclear antigen | 2.34554 |
| PLSCR3 | phospholipid scramblase 3 | 2.29907 |
| WDR11 | WD repeat domain 11 | 2.08884 |
| GLB1L | galactosidase, beta 1-like | 2.085 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 2.04621 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| ZNF586 | zinc finger protein 586 | -7.88053 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -7.78481 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.16564 |
| ADI1 | acireductone dioxygenase 1 | -4.58574 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.36396 |
| VDAC1 | voltage-dependent anion channel 1 | -3.84495 |
| COG2 | component of oligomeric golgi complex 2 | -3.70325 |
| ISOC1 | isochorismatase domain containing 1 | -3.48327 |
| CDC20 | cell division cycle 20 | -3.22147 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -3.10445 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.79722 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.68963 |
| CCNB2 | cyclin B2 | -2.60434 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.59634 |
| MTA1 | metastasis associated 1 | -2.50572 |
| ZNF134 | zinc finger protein 134 | -2.4562 |
| GOLT1B | golgi transport 1B | -2.39171 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.38037 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -2.35784 |
| TOR1A | torsin family 1, member A (torsin A) | -2.30251 |
| OPRK1 | opioid receptor, kappa 1 | -2.21645 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.18876 |
| SNX11 | sorting nexin 11 | -2.17231 |
| ZNF551 | zinc finger protein 551 | -2.07736 |
| PRPF4 | pre-mRNA processing factor 4 | -2.07675 |
| CHEK1 | checkpoint kinase 1 | -2.06957 |
| CETN3 | centrin, EF-hand protein, 3 | -2.02714 |
| RNF11 | ring finger protein 11 | -2.00606 |
