CRCGN012_HEPG2_24H:L12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tryptophan 1.25 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

929 genes differentially expressed following the CRCGN012_HEPG2_24H:L12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 10.0
RPL39L ribosomal protein L39-like 10.0
EPHB2 EPH receptor B2 9.39684
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 7.31078
ABHD6 abhydrolase domain containing 6 7.2028
SYNE2 spectrin repeat containing, nuclear envelope 2 6.67485
DENND2D DENN/MADD domain containing 2D 6.07155
CCDC85B coiled-coil domain containing 85B 6.0415
STIMATE STIM activating enhancer 5.9691
LOXL1 lysyl oxidase-like 1 5.79335
PRKCH protein kinase C, eta 5.75515
OXCT1 3-oxoacid CoA transferase 1 5.7341
STAP2 signal transducing adaptor family member 2 5.5226
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 5.4102
CCNF cyclin F 5.378
GAA glucosidase, alpha; acid 5.3658
TATDN2 TatD DNase domain containing 2 5.3255
MCOLN1 mucolipin 1 5.319
TBP TATA box binding protein 5.2794
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 5.24805
DDR1 discoidin domain receptor tyrosine kinase 1 5.24424
CARMIL1 capping protein regulator and myosin 1 linker 1 5.1068
SLC75A1 solute carrier family 75 member 1 5.0699
NOTCH1 notch 1 4.9586
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 4.9295
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.8878
SMIM40 small integral membrane protein 40 4.8335
CAPN1 calpain 1, (mu/I) large subunit 4.8249
BACE2 beta-site APP-cleaving enzyme 2 4.78175
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.75425
CHMP6 charged multivesicular body protein 6 4.6991
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.6982
UBQLN2 ubiquilin 2 4.673
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 4.60955
CDPF1 cysteine-rich, DPF motif domain containing 1 4.53725
CXCR4 chemokine (C-X-C motif) receptor 4 4.53113
INSIG1 insulin induced gene 1 4.5273
NR1H2 nuclear receptor subfamily 1, group H, member 2 4.5239
NELFA negative elongation factor complex member A 4.51958
ADRB2 adrenoceptor beta 2, surface 4.47745
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 4.3861
MELK maternal embryonic leucine zipper kinase 4.3751
TIAM1 T-cell lymphoma invasion and metastasis 1 4.34855
PCDHB11 protocadherin beta 11 4.28038
FZD7 frizzled class receptor 7 4.27225
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 4.22015
VAV3 vav 3 guanine nucleotide exchange factor 4.21665
CHAD chondroadherin 4.1708
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 4.1473
PPARG peroxisome proliferator-activated receptor gamma 4.10555
BTK Bruton agammaglobulinemia tyrosine kinase 4.0911
PEX11A peroxisomal biogenesis factor 11 alpha 4.01965
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.99095
CCL24 chemokine (C-C motif) ligand 24 3.93795
STXBP1 syntaxin binding protein 1 3.88365
TRPV4 transient receptor potential cation channel, subfamily V, member 4 3.8818
KIFBP kinesin family binding protein 3.8674
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 3.86625
DYNLT3 dynein, light chain, Tctex-type 3 3.7601
MAPK7 mitogen-activated protein kinase 7 3.53965
IL3RA interleukin 3 receptor, alpha (low affinity) 3.536
ADAM10 ADAM metallopeptidase domain 10 3.50645
NOX1 NADPH oxidase 1 3.50559
MAPK3 mitogen-activated protein kinase 3 3.496
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 3.4881
GLCE glucuronic acid epimerase 3.46325
CRYZL1 crystallin, zeta (quinone reductase)-like 1 3.4196
ATXN7L1 ataxin 7-like 1 3.4189
ADGRE5 adhesion G protein-coupled receptor E5 3.4082
LPAR2 lysophosphatidic acid receptor 2 3.39198
NANOS2 nanos homolog 2 (Drosophila) 3.3749
MARCHF2 membrane associated ring-CH-type finger 2 3.3516
TBXA2R thromboxane A2 receptor 3.34664
NEO1 neogenin 1 3.32905
GALR2 galanin receptor 2 3.32835
PHKG2 phosphorylase kinase, gamma 2 (testis) 3.31525
HDGFL3 HDGF like 3 3.2789
GATA3 GATA binding protein 3 3.23947
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) 3.21875
CPB1 carboxypeptidase B1 (tissue) 3.20955
CSK c-src tyrosine kinase 3.20945
PRSS22 protease, serine, 22 3.199
THBS4 thrombospondin 4 3.1897
CEP57 centrosomal protein 57kDa 3.17806
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 3.17675
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 3.16615
KIF14 kinesin family member 14 3.16455
GRK1 G protein-coupled receptor kinase 1 3.1572
GPER1 G protein-coupled estrogen receptor 1 3.1461
ATOH1 atonal homolog 1 (Drosophila) 3.1443
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 3.13285
FN3K fructosamine 3 kinase 3.1179
SP2 Sp2 transcription factor 3.1153
GHR growth hormone receptor 3.10615
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 3.10085
FBXL5 F-box and leucine-rich repeat protein 5 3.09193
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) 3.07505
RBM47 RNA binding motif protein 47 3.0511
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.04103
RNF146 ring finger protein 146 3.00715
KDM8 lysine (K)-specific demethylase 8 2.99995
SLC38A4 solute carrier family 38, member 4 2.99175
OLIG2 oligodendrocyte lineage transcription factor 2 2.98832
TLR4 toll-like receptor 4 2.9852
GRAMD4 GRAM domain containing 4 2.97895
SYTL3 synaptotagmin-like 3 2.9748
RNF11 ring finger protein 11 2.97225
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 2.972
GARRE1 granule associated Rac and RHOG effector 1 2.96275
CD3E CD3e molecule, epsilon (CD3-TCR complex) 2.96215
ZBTB39 zinc finger and BTB domain containing 39 2.9535
MLYCD malonyl-CoA decarboxylase 2.953
COL9A1 collagen, type IX, alpha 1 2.95065
SORBS3 sorbin and SH3 domain containing 3 2.94355
EVA1B eva-1 homolog B (C. elegans) 2.92975
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.92698
MATN4 matrilin 4 2.9254
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 2.9213
NSD2 nuclear receptor binding SET domain protein 2 2.89647
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 2.8954
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 2.87995
CCDC25 coiled-coil domain containing 25 2.8794
FKBP5 FK506 binding protein 5 2.8754
CRY2 cryptochrome circadian clock 2 2.87265
ELMO3 engulfment and cell motility 3 2.86715
SSTR1 somatostatin receptor 1 2.86245
CCDC85C coiled-coil domain containing 85C 2.8552
MAPK4 mitogen-activated protein kinase 4 2.855
SHOX short stature homeobox 2.85085
ETNK2 ethanolamine kinase 2 2.84775
GABPA GA binding protein transcription factor, alpha subunit 60kDa 2.84725
FCGRT Fc fragment of IgG, receptor, transporter, alpha 2.8461
LDAH lipid droplet associated hydrolase 2.84587
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 2.84515
PRR36 proline rich 36 2.8439
ZBTB7B zinc finger and BTB domain containing 7B 2.84285
FETUB fetuin B 2.8421
ARHGAP11A Rho GTPase activating protein 11A 2.8418
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 2.8355
KHK ketohexokinase (fructokinase) 2.83383
LMNB1 lamin B1 2.8234
KLC3 kinesin light chain 3 2.82315
ARPC4-TTLL3 ARPC4-TTLL3 readthrough 2.81573
SOCS2 suppressor of cytokine signaling 2 2.81215
BCL2L10 BCL2-like 10 (apoptosis facilitator) 2.8115
TRAPPC10 trafficking protein particle complex 10 2.80825
AFF3 AF4/FMR2 family, member 3 2.8077
PTTG1IP pituitary tumor-transforming 1 interacting protein 2.8062
PRKCG protein kinase C, gamma 2.806
MICB MHC class I polypeptide-related sequence B 2.7962
TEDC2 tubulin epsilon and delta complex 2 2.7954
DEPDC5 DEP domain containing 5 2.79325
L2HGDH L-2-hydroxyglutarate dehydrogenase 2.78905
POU3F3 POU class 3 homeobox 3 2.7877
JADE2 jade family PHD finger 2 2.78058
FRYL FRY-like 2.7653
XYLT2 xylosyltransferase II 2.75435
DCAF11 DDB1 and CUL4 associated factor 11 2.75388
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 2.746
LEF1 lymphoid enhancer-binding factor 1 2.74147
NSD1 nuclear receptor binding SET domain protein 1 2.741
ADRA1D adrenoceptor alpha 1D 2.73633
SP3 Sp3 transcription factor 2.73185
NR1I3 nuclear receptor subfamily 1, group I, member 3 2.7304
MAP7 microtubule-associated protein 7 2.72297
CYCS cytochrome c, somatic 2.72235
ACSM2A acyl-CoA synthetase medium-chain family member 2A 2.72195
AEBP1 AE binding protein 1 2.7204
BRDT bromodomain, testis-specific 2.71975
ZNF428 zinc finger protein 428 2.71415
DRD4 dopamine receptor D4 2.714
ADGRG1 adhesion G protein-coupled receptor G1 2.70755
CDC37L1 cell division cycle 37-like 1 2.7062
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 2.69535
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.69175
CD8A CD8a molecule 2.6805
KLF15 Kruppel-like factor 15 2.67625
EPN2 epsin 2 2.6677
OXT oxytocin/neurophysin I prepropeptide 2.6662
KIAA0232 KIAA0232 2.6638
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 2.66275
CDX4 caudal type homeobox 4 2.6619
WDR62 WD repeat domain 62 2.6553
RAB28 RAB28, member RAS oncogene family 2.6535
WNT7B wingless-type MMTV integration site family, member 7B 2.65135
KLRC1 killer cell lectin-like receptor subfamily C, member 1 2.65
CCDC88C coiled-coil domain containing 88C 2.64945
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.64365
CMA1 chymase 1, mast cell 2.6429
RBM38 RNA binding motif protein 38 2.6424
CNTFR ciliary neurotrophic factor receptor 2.6398
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 2.6394
ADIRF adipogenesis regulatory factor 2.6365
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 2.6284
POM121 POM121 transmembrane nucleoporin 2.62685
FAM193A family with sequence similarity 193, member A 2.62625
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.62415
USP11 ubiquitin specific peptidase 11 2.62025
TM7SF2 transmembrane 7 superfamily member 2 2.6202
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 2.61665
LRRN2 leucine rich repeat neuronal 2 2.6154
AIG1 androgen-induced 1 2.6114
COL6A2 collagen, type VI, alpha 2 2.61017
ZNHIT2 zinc finger, HIT-type containing 2 2.6099
FRY furry homolog (Drosophila) 2.6074
TLR2 toll-like receptor 2 2.6063
COL11A2 collagen, type XI, alpha 2 2.60547
TPK1 thiamin pyrophosphokinase 1 2.6046
CGRRF1 cell growth regulator with ring finger domain 1 2.604
THRA thyroid hormone receptor, alpha 2.60371
ZBTB7C zinc finger and BTB domain containing 7C 2.59085
CNPY3 canopy FGF signaling regulator 3 2.5898
MBNL1 muscleblind-like splicing regulator 1 2.58971
CNMD chondromodulin 2.58575
CTIF CBP80/20-dependent translation initiation factor 2.5829
CD247 CD247 molecule 2.5822
CCDC81 coiled-coil domain containing 81 2.58215
FANCE Fanconi anemia, complementation group E 2.57915
SMAD3 SMAD family member 3 2.57795
SLC22A17 solute carrier family 22, member 17 2.56595
EPHX3 epoxide hydrolase 3 2.56405
ULK1 unc-51 like autophagy activating kinase 1 2.56235
EVX1 even-skipped homeobox 1 2.5622
ZNF358 zinc finger protein 358 2.5622
INPP5J inositol polyphosphate-5-phosphatase J 2.5527
CHERP calcium homeostasis endoplasmic reticulum protein 2.55015
CTBP1 C-terminal binding protein 1 2.54895
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa 2.54725
ZBTB25 zinc finger and BTB domain containing 25 2.5456
HPX hemopexin 2.54528
HPR haptoglobin-related protein 2.54465
MATN1 matrilin 1, cartilage matrix protein 2.54367
MED31 mediator complex subunit 31 2.5397
OSBP2 oxysterol binding protein 2 2.5379
MAP3K5 mitogen-activated protein kinase kinase kinase 5 2.53618
GPN3 GPN-loop GTPase 3 2.5341
CAPRIN1 cell cycle associated protein 1 2.52585
WNT16 wingless-type MMTV integration site family, member 16 2.52345
HIP1R huntingtin interacting protein 1 related 2.52182
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 2.52055
ADD1 adducin 1 (alpha) 2.5179
PNPLA6 patatin-like phospholipase domain containing 6 2.51355
EML2 echinoderm microtubule associated protein like 2 2.51117
C8B complement component 8, beta polypeptide 2.5066
PCOLCE2 procollagen C-endopeptidase enhancer 2 2.5055
SBNO2 strawberry notch homolog 2 (Drosophila) 2.5053
IDUA iduronidase, alpha-L- 2.50515
TPD52L1 tumor protein D52-like 1 2.50388
LRP10 low density lipoprotein receptor-related protein 10 2.4909
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 2.489
BRMS1L breast cancer metastasis-suppressor 1-like 2.48205
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 2.47412
RIC8B RIC8 guanine nucleotide exchange factor B 2.472
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 2.47172
CBARP CACN subunit beta associated regulatory protein 2.47035
ADAM11 ADAM metallopeptidase domain 11 2.4701
RAB26 RAB26, member RAS oncogene family 2.46823
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 2.46815
FGGY FGGY carbohydrate kinase domain containing 2.46515
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 2.4646
DHRS4 dehydrogenase/reductase (SDR family) member 4 2.4644
PKN1 protein kinase N1 2.4616
ADPRH ADP-ribosylarginine hydrolase 2.45875
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 2.4568
EID1 EP300 interacting inhibitor of differentiation 1 2.45315
DAND5 DAN domain family member 5, BMP antagonist 2.4524
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 2.4524
NOD2 nucleotide-binding oligomerization domain containing 2 2.4524
STATH statherin 2.45125
PARM1 prostate androgen-regulated mucin-like protein 1 2.4497
MAN2B2 mannosidase, alpha, class 2B, member 2 2.44925
KIF5C kinesin family member 5C 2.4466
TGIF1 TGFB-induced factor homeobox 1 2.4463
NTN3 netrin 3 2.4447
FGF8 fibroblast growth factor 8 (androgen-induced) 2.4443
FBXO38 F-box protein 38 2.44145
HEYL hes-related family bHLH transcription factor with YRPW motif-like 2.4369
FBXO24 F-box protein 24 2.42785
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 2.42755
GZMM granzyme M (lymphocyte met-ase 1) 2.426
VGLL4 vestigial-like family member 4 2.42517
PLEKHA6 pleckstrin homology domain containing, family A member 6 2.42485
FNDC11 fibronectin type III domain containing 11 2.42175
NDC80 NDC80 kinetochore complex component 2.4214
EZR ezrin 2.4181
TSC22D3 TSC22 domain family, member 3 2.41595
C1RL complement component 1, r subcomponent-like 2.4157
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.4153
ARHGAP4 Rho GTPase activating protein 4 2.4125
MRFAP1L1 Morf4 family associated protein 1-like 1 2.41205
HLX H2.0-like homeobox 2.40975
SLC66A3 solute carrier family 66 member 3 2.4091
ALOX5 arachidonate 5-lipoxygenase 2.40475
PAX1 paired box 1 2.40385
SQOR sulfide quinone oxidoreductase 2.40375
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 2.39985
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 2.3983
SIGLEC9 sialic acid binding Ig-like lectin 9 2.39665
CELF2 CUGBP, Elav-like family member 2 2.39495
E2F8 E2F transcription factor 8 2.39415
METTL4 methyltransferase like 4 2.39185
MMP23B matrix metallopeptidase 23B 2.39125
GRAP2 GRB2-related adaptor protein 2 2.3891
SHH sonic hedgehog 2.3883
CALCB calcitonin-related polypeptide beta 2.38715
SPRED2 sprouty-related, EVH1 domain containing 2 2.38618
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.38497
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.38475
LMX1B LIM homeobox transcription factor 1, beta 2.3834
IREB2 iron-responsive element binding protein 2 2.3806
KDM4D lysine (K)-specific demethylase 4D 2.38
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 2.37575
RARA retinoic acid receptor, alpha 2.37532
IL4 interleukin 4 2.37285
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.3727
RASA4 RAS p21 protein activator 4 2.371
SOD1 superoxide dismutase 1, soluble 2.3676
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 2.36255
RBM15B RNA binding motif protein 15B 2.3616
RMC1 regulator of MON1-CCZ1 2.36075
EXO1 exonuclease 1 2.3579
CCDC134 coiled-coil domain containing 134 2.3561
FOXD2 forkhead box D2 2.35105
EPHA3 EPH receptor A3 2.34732
ATAD5 ATPase family, AAA domain containing 5 2.3472
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2.34718
CTR9 CTR9, Paf1/RNA polymerase II complex component 2.34595
PIAS4 protein inhibitor of activated STAT, 4 2.34535
C8A complement component 8, alpha polypeptide 2.33885
NKG7 natural killer cell granule protein 7 2.33845
MTM1 myotubularin 1 2.33562
AGXT alanine-glyoxylate aminotransferase 2.3339
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 2.33225
PRELP proline/arginine-rich end leucine-rich repeat protein 2.33125
CYB5R2 cytochrome b5 reductase 2 2.3293
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 2.32762
YIPF3 Yip1 domain family, member 3 2.3256
PLA2G2E phospholipase A2, group IIE 2.32525
HAO2 hydroxyacid oxidase 2 (long chain) 2.3247
TNP1 transition protein 1 (during histone to protamine replacement) 2.32225
KIF15 kinesin family member 15 2.3214
C8G complement component 8, gamma polypeptide 2.32125
IKZF4 IKAROS family zinc finger 4 (Eos) 2.32015
TPSD1 tryptase delta 1 2.31985
ANGPTL7 angiopoietin-like 7 2.315
GJA8 gap junction protein, alpha 8, 50kDa 2.3145
ACADSB acyl-CoA dehydrogenase, short/branched chain 2.3126
CPT1A carnitine palmitoyltransferase 1A (liver) 2.31251
SULF1 sulfatase 1 2.31222
KLRD1 killer cell lectin-like receptor subfamily D, member 1 2.31138
CNTN2 contactin 2 (axonal) 2.3076
ADM2 adrenomedullin 2 2.3066
GPM6A glycoprotein M6A 2.30603
HIP1 huntingtin interacting protein 1 2.30573
PDCD1 programmed cell death 1 2.30495
SLC43A3 solute carrier family 43, member 3 2.30457
ADGRB1 adhesion G protein-coupled receptor B1 2.3043
FAT4 FAT atypical cadherin 4 2.3034
KISS1 KiSS-1 metastasis-suppressor 2.3019
CHD8 chromodomain helicase DNA binding protein 8 2.30155
LHX5 LIM homeobox 5 2.30135
RGS14 regulator of G-protein signaling 14 2.2998
DNM2 dynamin 2 2.29665
CASP5 caspase 5, apoptosis-related cysteine peptidase 2.29635
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 2.2864
RAB3A RAB3A, member RAS oncogene family 2.28605
BICRAL BICRA like chromatin remodeling complex associated protein 2.28592
IL10RB interleukin 10 receptor, beta 2.2681
KLRC4-KLRK1 KLRC4-KLRK1 readthrough 2.26335
COMP cartilage oligomeric matrix protein 2.2632
CLDN14 claudin 14 2.263
SKA1 spindle and kinetochore associated complex subunit 1 2.26225
CDC25A cell division cycle 25A 2.26185
CDHR1 cadherin-related family member 1 2.2614
CSPG4 chondroitin sulfate proteoglycan 4 2.25868
MGA MGA, MAX dimerization protein 2.25685
PCNX1 pecanex 1 2.2554
TRIM62 tripartite motif containing 62 2.25502
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.2535
GPR68 G protein-coupled receptor 68 2.2481
PKLR pyruvate kinase, liver and RBC 2.24717
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 2.24475
CT55 cancer/testis antigen 55 2.24415
H2BC9 H2B clustered histone 9 2.24375
ICAM5 intercellular adhesion molecule 5, telencephalin 2.2422
AIDA axin interactor, dorsalization associated 2.2422
GJA3 gap junction protein, alpha 3, 46kDa 2.2409
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 2.2399
KIF17 kinesin family member 17 2.2393
TRAM2 translocation associated membrane protein 2 2.23907
LMAN1L lectin, mannose-binding, 1 like 2.2374
NRDE2 NRDE-2, necessary for RNA interference, domain containing 2.2372
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 2.237
BGN biglycan 2.23265
CDK4 cyclin-dependent kinase 4 2.23145
KLRC3 killer cell lectin-like receptor subfamily C, member 3 2.22925
NHLH1 nescient helix loop helix 1 2.2286
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 2.2285
FKBP8 FK506 binding protein 8, 38kDa 2.2269
IRF2 interferon regulatory factor 2 2.22465
TBX21 T-box 21 2.222
DGKH diacylglycerol kinase, eta 2.22175
CSDC2 cold shock domain containing C2, RNA binding 2.2212
CAMK1 calcium/calmodulin-dependent protein kinase I 2.2194
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 2.21935
REL v-rel avian reticuloendotheliosis viral oncogene homolog 2.2192
MMP2 matrix metallopeptidase 2 2.21895
NGB neuroglobin 2.2187
PAAF1 proteasomal ATPase-associated factor 1 2.21555
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 2.21525
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 2.21498
CCL2 chemokine (C-C motif) ligand 2 2.2147
TMSB4Y thymosin beta 4, Y-linked 2.21265
CXCR3 chemokine (C-X-C motif) receptor 3 2.21187
VTN vitronectin 2.21075
MN1 meningioma (disrupted in balanced translocation) 1 2.2105
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 2.21045
CLEC2D C-type lectin domain family 2, member D 2.20875
LY6G6F-LY6G6D LY6G6F-LY6G6D readthrough 2.2085
SOCS3 suppressor of cytokine signaling 3 2.2066
NOTCH2 notch 2 2.20487
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 2.2046
TUBB6 tubulin, beta 6 class V 2.2029
PCDHGB6 protocadherin gamma subfamily B, 6 2.20098
NRF1 nuclear respiratory factor 1 2.20057
GPATCH1 G patch domain containing 1 2.20015
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 2.19925
PSMC3IP PSMC3 interacting protein 2.19793
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae) 2.196
ZNF141 zinc finger protein 141 2.19425
RRAGB Ras-related GTP binding B 2.19405
ETFDH electron-transferring-flavoprotein dehydrogenase 2.18998
GLUL glutamate-ammonia ligase 2.18903
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 2.18835
GRIK4 glutamate receptor, ionotropic, kainate 4 2.1882
DTX3 deltex 3, E3 ubiquitin ligase 2.18767
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 2.187
MYL7 myosin, light chain 7, regulatory 2.1864
MASP2 mannan-binding lectin serine peptidase 2 2.18213
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 2.17937
PDE1B phosphodiesterase 1B, calmodulin-dependent 2.17885
EDN2 endothelin 2 2.175
KANK3 KN motif and ankyrin repeat domains 3 2.1743
CPPED1 calcineurin-like phosphoesterase domain containing 1 2.173
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 2.16832
APOBR apolipoprotein B receptor 2.1676
LOC128966622 putative protein N-methyltransferase FAM86B2 2.1672
DNA2 DNA replication helicase/nuclease 2 2.1637
EYA1 EYA transcriptional coactivator and phosphatase 1 2.1595
TMEM14A transmembrane protein 14A 2.15915
HOXD9 homeobox D9 2.1586
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 2.15826
ZYX zyxin 2.15223
BCOR BCL6 corepressor 2.15205
KRCC1 lysine-rich coiled-coil 1 2.1503
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 2.1499
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 2.14798
RAB1B RAB1B, member RAS oncogene family 2.14655
BCL7B B-cell CLL/lymphoma 7B 2.14585
SRF serum response factor (c-fos serum response element-binding transcription factor) 2.1442
PTBP3 polypyrimidine tract binding protein 3 2.1433
FAM53B family with sequence similarity 53, member B 2.14267
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 2.14175
MAGEC2 melanoma antigen family C2 2.141
IL5 interleukin 5 2.1389
WDR43 WD repeat domain 43 2.1382
PPP4R3A protein phosphatase 4 regulatory subunit 3A 2.13665
DPYS dihydropyrimidinase 2.13645
MMP17 matrix metallopeptidase 17 (membrane-inserted) 2.13545
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa 2.1331
WHR1 winged helix repair factor 1 2.13092
ARL15 ADP-ribosylation factor-like 15 2.13025
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 2.1293
ACAN aggrecan 2.12878
MEGF6 multiple EGF-like-domains 6 2.12785
CLPTM1 cleft lip and palate associated transmembrane protein 1 2.12515
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 2.1226
ZBTB14 zinc finger and BTB domain containing 14 2.12217
EVL Enah/Vasp-like 2.12215
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 2.11965
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 2.11875
CAMK1D calcium/calmodulin-dependent protein kinase ID 2.11685
TMA16 translation machinery associated 16 homolog (S. cerevisiae) 2.11525
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.11475
PCDHA10 protocadherin alpha 10 2.11435
CDHR5 cadherin-related family member 5 2.11433
ABHD8 abhydrolase domain containing 8 2.1138
GRAPL GRB2-related adaptor protein-like 2.1114
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 2.1106
MAP3K20 mitogen-activated protein kinase kinase kinase 20 2.1103
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 2.10962
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit 2.1094
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 2.10742
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 2.107
LNPEP leucyl/cystinyl aminopeptidase 2.10685
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 2.10395
PPARD peroxisome proliferator-activated receptor delta 2.10357
JAK2 Janus kinase 2 2.10195
NCBP3 nuclear cap binding subunit 3 2.1015
H1-3 H1.3 linker histone, cluster member 2.0978
ZNF180 zinc finger protein 180 2.09745
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.09678
CPAP centrosome assembly and centriole elongation protein 2.0962
CRYGC crystallin, gamma C 2.096
SCARA3 scavenger receptor class A, member 3 2.09535
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 2.0953
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 2.0927
CCL4 chemokine (C-C motif) ligand 4 2.09195
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 2.0919
FZD8 frizzled class receptor 8 2.0916
ACOT7 acyl-CoA thioesterase 7 2.0916
ZNF654 zinc finger protein 654 2.09092
NMUR1 neuromedin U receptor 1 2.08935
LPO lactoperoxidase 2.08715
UPB1 ureidopropionase, beta 2.08665
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 2.0862
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa 2.08595
LIME1 Lck interacting transmembrane adaptor 1 2.0859
COL4A1 collagen, type IV, alpha 1 2.08523
TCF20 transcription factor 20 (AR1) 2.0847
ZNF528 zinc finger protein 528 2.08465
BRAF B-Raf proto-oncogene, serine/threonine kinase 2.08385
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 2.0822
PDE4B phosphodiesterase 4B, cAMP-specific 2.08103
AANAT aralkylamine N-acetyltransferase 2.0808
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.07985
MVP major vault protein 2.0797
WNT4 wingless-type MMTV integration site family, member 4 2.0791
EPHB6 EPH receptor B6 2.0782
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 2.07775
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 2.077
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 2.07675
NPIPB6 nuclear pore complex interacting protein family, member B6 2.07615
TAC4 tachykinin 4 (hemokinin) 2.0758
UST uronyl-2-sulfotransferase 2.0753
ZC4H2 zinc finger, C4H2 domain containing 2.07395
NFYB nuclear transcription factor Y, beta 2.07342
SYTL2 synaptotagmin-like 2 2.0725
TYW2 tRNA wybutosine-synthesizing protein 2 2.0707
COPS7A COP9 signalosome subunit 7A 2.0695
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 2.06925
LRRC41 leucine rich repeat containing 41 2.06912
FOXO3 forkhead box O3 2.06829
ABR active BCR-related 2.06682
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 2.065
ANKFY1 ankyrin repeat and FYVE domain containing 1 2.06445
LOC107987479 cytochrome P450 2D6 2.0642
ZBTB48 zinc finger and BTB domain containing 48 2.06395
CILK1 ciliogenesis associated kinase 1 2.0639
PID1 phosphotyrosine interaction domain containing 1 2.06365
CD6 CD6 molecule 2.06171
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 2.06095
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 2.06065
TRAK2 trafficking protein, kinesin binding 2 2.05783
CIDEA cell death-inducing DFFA-like effector a 2.0568
ZEB2 zinc finger E-box binding homeobox 2 2.05675
LOC122526780 uncharacterized LOC122526780 2.056
RAB30 RAB30, member RAS oncogene family 2.05465
ARID5A AT rich interactive domain 5A (MRF1-like) 2.0515
MMP3 matrix metallopeptidase 3 2.04955
OVOL1 ovo-like zinc finger 1 2.04895
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 2.04887
ICAM1 intercellular adhesion molecule 1 2.04878
QRICH1 glutamine-rich 1 2.0474
RAB4B RAB4B, member RAS oncogene family 2.0471
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 2.04525
CAPN5 calpain 5 2.0435
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 2.04345
FCHO1 FCH domain only 1 2.0418
CTSS cathepsin S 2.04152
MROH7 maestro heat-like repeat family member 7 2.04125
TESMIN testis expressed metallothionein like protein 2.0411
ZDHHC13 zinc finger, DHHC-type containing 13 2.04095
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 2.0407
PINK1 PTEN induced putative kinase 1 2.04045
PER1 period circadian clock 1 2.04007
TNRC6B trinucleotide repeat containing 6B 2.03915
SH3YL1 SH3 and SYLF domain containing 1 2.0388
CNPY3-GNMT CNPY3-GNMT readthrough 2.0368
PCDHB13 protocadherin beta 13 2.0358
GLRX glutaredoxin (thioltransferase) 2.0356
COL13A1 collagen, type XIII, alpha 1 2.0342
JRKL JRK-like 2.0325
ZNF423 zinc finger protein 423 2.0303
HMHB1 histocompatibility (minor) HB-1 2.0291
CATSPERG catsper channel auxiliary subunit gamma 2.029
CREBBP CREB binding protein 2.0283
LOC124906280 uncharacterized LOC124906280 2.0268
TOP3B topoisomerase (DNA) III beta 2.02663
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 2.02555
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 2.025
SBF1 SET binding factor 1 2.02439
SPAG1 sperm associated antigen 1 2.02435
GCGR glucagon receptor 2.02395
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 2.02343
NFE2L2 nuclear factor, erythroid 2-like 2 2.0216
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 2.02125
PCGF3 polycomb group ring finger 3 2.0209
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 2.0208
NCOA3 nuclear receptor coactivator 3 2.01998
ANGPTL4 angiopoietin-like 4 2.0195
EGR3 early growth response 3 2.0189
CCKAR cholecystokinin A receptor 2.0185
LAG3 lymphocyte-activation gene 3 2.0181
OPRL1 opiate receptor-like 1 2.01783
TPBG trophoblast glycoprotein 2.01665
TRPM6 transient receptor potential cation channel, subfamily M, member 6 2.01645
TBC1D10C TBC1 domain family, member 10C 2.0152
GATAD2A GATA zinc finger domain containing 2A 2.0148
PLD3 phospholipase D family, member 3 2.0143
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 2.0135
CASS4 Cas scaffolding protein family member 4 2.01315
MFSD1 major facilitator superfamily domain containing 1 2.01275
BAAT bile acid CoA:amino acid N-acyltransferase 2.01205
S100A5 S100 calcium binding protein A5 2.0114
FES FES proto-oncogene, tyrosine kinase 2.01125
HSPB2 heat shock 27kDa protein 2 2.0103
FOCAD focadhesin 2.01025
TCP11 t-complex 11, testis-specific 2.0102
ARSA arylsulfatase A 2.00985
SFMBT1 Scm-like with four mbt domains 1 2.0096
DRP2 dystrophin related protein 2 2.00955
GRM2 glutamate receptor, metabotropic 2 2.00925
KCNK12 potassium channel, two pore domain subfamily K, member 12 2.0082
HOOK2 hook microtubule-tethering protein 2 2.00785
IL18BP interleukin 18 binding protein 2.00693
FAM20B family with sequence similarity 20, member B 2.00688
TNIP3 TNFAIP3 interacting protein 3 2.00475
HOXA3 homeobox A3 2.00395
CDC50A cell division cycle 50 P4-ATPase accessory subunit A 2.0017
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 2.0014

decreased expression

Symbol Name Standardized Value
MRPS2 mitochondrial ribosomal protein S2 -10.0
TRIB3 tribbles pseudokinase 3 -10.0
TARBP1 TAR (HIV-1) RNA binding protein 1 -10.0
CCNB2 cyclin B2 -8.7701
PCNA proliferating cell nuclear antigen -7.98285
GNAS GNAS complex locus -7.51483
PEG10 paternally expressed 10 -6.94085
GTPBP8 GTP-binding protein 8 (putative) -6.25095
CRYZ crystallin, zeta (quinone reductase) -5.90145
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -5.8875
VDAC1 voltage-dependent anion channel 1 -5.74615
HMG20B high mobility group 20B -5.64673
DSG2 desmoglein 2 -5.26975
DNM1L dynamin 1-like -5.1806
UBE3C ubiquitin protein ligase E3C -5.15905
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -5.0455
GDF15 growth differentiation factor 15 -5.0
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.9376
MRPS16 mitochondrial ribosomal protein S16 -4.85475
PECR peroxisomal trans-2-enoyl-CoA reductase -4.78555
MRPL58 mitochondrial ribosomal protein L58 -4.773
CCNB1 cyclin B1 -4.74085
LOC124907782 dual specificity protein phosphatase 22 -4.6834
CDC20 cell division cycle 20 -4.6684
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.66275
NUP85 nucleoporin 85kDa -4.6249
LDHD lactate dehydrogenase D -4.60435
FBXL12 F-box and leucine-rich repeat protein 12 -4.57165
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -4.57005
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.5595
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.5505
TSPAN4 tetraspanin 4 -4.46187
CD320 CD320 molecule -4.43735
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -4.3449
ITGB1BP1 integrin beta 1 binding protein 1 -4.30737
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.2944
FASTKD5 FAST kinase domains 5 -4.25115
VAT1 vesicle amine transport 1 -4.2345
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.2286
PLK1 polo-like kinase 1 -4.22195
TM9SF2 transmembrane 9 superfamily member 2 -4.1776
DERA deoxyribose-phosphate aldolase (putative) -4.14435
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -4.1322
NGRN neugrin, neurite outgrowth associated -4.12375
CDC25B cell division cycle 25B -4.10955
C2CD5 C2 calcium-dependent domain containing 5 -4.10545
CRELD2 cysteine-rich with EGF-like domains 2 -4.0524
ELAC2 elaC ribonuclease Z 2 -3.9706
TCTN1 tectonic family member 1 -3.9537
NR0B2 nuclear receptor subfamily 0, group B, member 2 -3.89055
FAIM Fas apoptotic inhibitory molecule -3.88245
TLCD3A TLC domain containing 3A -3.85815
ZW10 zw10 kinetochore protein -3.8558
MYLK myosin light chain kinase -3.78985
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.77865
MAN1B1 mannosidase, alpha, class 1B, member 1 -3.69222
EGF epidermal growth factor -3.63845
LAGE3 L antigen family, member 3 -3.6275
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -3.59345
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -3.5909
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.56915
KLHL21 kelch-like family member 21 -3.49705
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -3.4615
MRPS7 mitochondrial ribosomal protein S7 -3.4257
CHMP4B charged multivesicular body protein 4B -3.40375
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -3.3894
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -3.36968
GTF3A general transcription factor IIIA -3.35777
RGS2 regulator of G-protein signaling 2 -3.3498
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -3.34625
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.3412
GOLGA8A golgin A8 family, member A -3.1853
UBAP2 ubiquitin associated protein 2 -3.1796
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -3.16928
OXA1L oxidase (cytochrome c) assembly 1-like -3.15735
PHKA1 phosphorylase kinase, alpha 1 (muscle) -3.1133
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -3.113
MAIP1 matrix AAA peptidase interacting protein 1 -3.0848
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.98185
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 -2.9557
NME2 NME/NM23 nucleoside diphosphate kinase 2 -2.95505
FAM53C family with sequence similarity 53, member C -2.94845
PDLIM1 PDZ and LIM domain 1 -2.93625
ADSL adenylosuccinate lyase -2.9297
EXOSC8 exosome component 8 -2.9076
EHBP1 EH domain binding protein 1 -2.89845
POLR2H polymerase (RNA) II (DNA directed) polypeptide H -2.8809
ACAA1 acetyl-CoA acyltransferase 1 -2.88022
NXN nucleoredoxin -2.87315
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -2.824
ANKRD10 ankyrin repeat domain 10 -2.7988
RWDD1 RWD domain containing 1 -2.7474
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -2.7461
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 -2.73185
SSNA1 Sjogren syndrome nuclear autoantigen 1 -2.72865
TARBP2 TAR (HIV-1) RNA binding protein 2 -2.7265
AHCY adenosylhomocysteinase -2.7261
E2F6 E2F transcription factor 6 -2.7252
OSBPL9 oxysterol binding protein-like 9 -2.7091
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.69725
NXT1 nuclear transport factor 2-like export factor 1 -2.6857
BTBD3 BTB (POZ) domain containing 3 -2.68495
NRIP1 nuclear receptor interacting protein 1 -2.68047
CTNND1 catenin (cadherin-associated protein), delta 1 -2.67777
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.6678
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -2.65252
ATF4 activating transcription factor 4 -2.65085
EIF3B eukaryotic translation initiation factor 3, subunit B -2.65035
KIZ kizuna centrosomal protein -2.64535
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.6419
RFC2 replication factor C (activator 1) 2, 40kDa -2.62652
CCP110 centriolar coiled coil protein 110kDa -2.6203
EIF3CL eukaryotic translation initiation factor 3, subunit C-like -2.61207
TUFM Tu translation elongation factor, mitochondrial -2.60125
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast) -2.596
FAM50A family with sequence similarity 50, member A -2.5807
ANAPC1 anaphase promoting complex subunit 1 -2.58035
TMED3 transmembrane emp24 protein transport domain containing 3 -2.5697
ENTR1 endosome associated trafficking regulator 1 -2.5645
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -2.55795
ALAS1 5'-aminolevulinate synthase 1 -2.55445
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.5479
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -2.54605
MUC6 mucin 6, oligomeric mucus/gel-forming -2.54045
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) -2.534
MRPS11 mitochondrial ribosomal protein S11 -2.52398
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 -2.50665
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -2.5011
CASP7 caspase 7, apoptosis-related cysteine peptidase -2.49585
PEG3 paternally expressed 3 -2.4842
NCKAP1 NCK-associated protein 1 -2.4805
RHOBTB1 Rho-related BTB domain containing 1 -2.47905
PTCD3 pentatricopeptide repeat domain 3 -2.47775
EXT1 exostosin glycosyltransferase 1 -2.47445
RNF220 ring finger protein 220 -2.47295
RBM5 RNA binding motif protein 5 -2.46723
HLA-DMB major histocompatibility complex, class II, DM beta -2.46615
FASTKD3 FAST kinase domains 3 -2.46485
NKRF NFKB repressing factor -2.45195
PRR7 proline rich 7 (synaptic) -2.4445
TPST1 tyrosylprotein sulfotransferase 1 -2.43825
UCKL1 uridine-cytidine kinase 1-like 1 -2.41645
EIF3I eukaryotic translation initiation factor 3, subunit I -2.41275
UPP1 uridine phosphorylase 1 -2.4105
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 -2.40882
HEBP1 heme binding protein 1 -2.40585
MRPL46 mitochondrial ribosomal protein L46 -2.39995
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 -2.39595
POGLUT2 protein O-glucosyltransferase 2 -2.39185
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -2.38972
SMAD5 SMAD family member 5 -2.38085
RPL9 ribosomal protein L9 -2.37715
RTCA RNA 3'-terminal phosphate cyclase -2.377
KPNA3 karyopherin alpha 3 (importin alpha 4) -2.37507
RPS27L ribosomal protein S27-like -2.37285
TMEM214 transmembrane protein 214 -2.36765
SH3GL1 SH3-domain GRB2-like 1 -2.363
PDCD6 programmed cell death 6 -2.3624
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.36025
PLEKHA5 pleckstrin homology domain containing, family A member 5 -2.35245
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -2.35162
PRDX1 peroxiredoxin 1 -2.3485
NME1 NME/NM23 nucleoside diphosphate kinase 1 -2.34545
LIPF lipase, gastric -2.33595
MDH1 malate dehydrogenase 1, NAD (soluble) -2.3347
IFRD2 interferon-related developmental regulator 2 -2.33075
NVL nuclear VCP-like -2.32265
NOL11 nucleolar protein 11 -2.3217
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 -2.32055
G6PC3 glucose 6 phosphatase, catalytic, 3 -2.3185
PPP1R9A protein phosphatase 1, regulatory subunit 9A -2.3134
CTSC cathepsin C -2.3097
FFAR1 free fatty acid receptor 1 -2.3087
SSBP2 single-stranded DNA binding protein 2 -2.30657
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -2.30605
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.3021
VAMP7 vesicle-associated membrane protein 7 -2.29845
RPL10A ribosomal protein L10a -2.29635
APRT adenine phosphoribosyltransferase -2.2959
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma -2.2938
RANGRF RAN guanine nucleotide release factor -2.29265
RCC1L RCC1 like -2.2896
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -2.28905
SNAP29 synaptosomal-associated protein, 29kDa -2.2773
LAMB1 laminin, beta 1 -2.27513
EDF1 endothelial differentiation-related factor 1 -2.26765
IST1 increased sodium tolerance 1 homolog (yeast) -2.2668
SMG8 SMG8 nonsense mediated mRNA decay factor -2.26675
MRPL57 mitochondrial ribosomal protein L57 -2.25498
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.2548
RPS3A ribosomal protein S3A -2.25128
BICD1 bicaudal D homolog 1 (Drosophila) -2.24895
UBC ubiquitin C -2.24505
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.2443
SNX11 sorting nexin 11 -2.23773
REEP5 receptor accessory protein 5 -2.23723
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -2.2354
ZNF593 zinc finger protein 593 -2.2352
METTL25B methyltransferase like 25B -2.2292
IARS1 isoleucyl-tRNA synthetase 1 -2.22345
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -2.21625
RPS4X ribosomal protein S4, X-linked -2.2136
PFDN2 prefoldin subunit 2 -2.21125
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -2.2112
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.20967
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.2076
MOSPD1 motile sperm domain containing 1 -2.2045
EMC8 ER membrane protein complex subunit 8 -2.20385
EXD2 exonuclease 3'-5' domain containing 2 -2.19925
ENC1 ectodermal-neural cortex 1 (with BTB domain) -2.1957
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -2.19185
PRPF4 pre-mRNA processing factor 4 -2.18963
RPS10 ribosomal protein S10 -2.18267
ANAPC5 anaphase promoting complex subunit 5 -2.18244
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -2.1818
GLB1 galactosidase, beta 1 -2.17495
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) -2.16525
BOLA2B bolA family member 2B -2.16225
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -2.1582
MRPL23 mitochondrial ribosomal protein L23 -2.1571
SATB1 SATB homeobox 1 -2.157
TIPRL TOR signaling pathway regulator -2.1558
SLIRP SRA stem-loop interacting RNA binding protein -2.1522
WDR12 WD repeat domain 12 -2.15165
PARN poly(A)-specific ribonuclease -2.1443
RSRP1 arginine/serine-rich protein 1 -2.1384
DKC1 dyskeratosis congenita 1, dyskerin -2.13602
INTS3 integrator complex subunit 3 -2.1354
CHKA choline kinase alpha -2.13483
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.1347
UQCRH ubiquinol-cytochrome c reductase hinge protein -2.1334
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4 -2.132
SESN1 sestrin 1 -2.1295
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.1268
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 -2.12532
EIF2D eukaryotic translation initiation factor 2D -2.12215
CDC16 cell division cycle 16 -2.11798
FNTA farnesyltransferase, CAAX box, alpha -2.11548
RPL12 ribosomal protein L12 -2.1122
RPL41 ribosomal protein L41 -2.107
SPRYD7 SPRY domain containing 7 -2.1046
PTK7 protein tyrosine kinase 7 (inactive) -2.10415
RPLP1 ribosomal protein, large, P1 -2.10405
MPHOSPH6 M-phase phosphoprotein 6 -2.10125
SYNC syncoilin, intermediate filament protein -2.10035
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -2.09872
DEPTOR DEP domain containing MTOR-interacting protein -2.0963
SPATS2 spermatogenesis associated, serine-rich 2 -2.0887
DENR density-regulated protein -2.08815
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -2.0872
CAPN3 calpain 3, (p94) -2.08617
METTL22 methyltransferase like 22 -2.08575
TPT1 tumor protein, translationally-controlled 1 -2.08442
ZNF133 zinc finger protein 133 -2.08397
AK4 adenylate kinase 4 -2.0831
A2M alpha-2-macroglobulin -2.08285
PTBP1 polypyrimidine tract binding protein 1 -2.08238
IMP4 IMP4, U3 small nucleolar ribonucleoprotein -2.08035
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -2.0739
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -2.0673
NT5DC2 5'-nucleotidase domain containing 2 -2.06445
NOP56 NOP56 ribonucleoprotein -2.06325
ZNF345 zinc finger protein 345 -2.06225
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 -2.0609
RPL38 ribosomal protein L38 -2.0557
LCMT1 leucine carboxyl methyltransferase 1 -2.0556
ARID5B AT rich interactive domain 5B (MRF1-like) -2.0544
TUBA1B tubulin, alpha 1b -2.0538
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -2.0498
RPS27 ribosomal protein S27 -2.0461
HLA-DOB major histocompatibility complex, class II, DO beta -2.0451
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -2.044
CZIB CXXC motif containing zinc binding protein -2.04385
ITM2B integral membrane protein 2B -2.04233
RPLP0 ribosomal protein, large, P0 -2.042
NANS N-acetylneuraminic acid synthase -2.03915
FJX1 four jointed box 1 (Drosophila) -2.0388
TSKU tsukushi, small leucine rich proteoglycan -2.03545
SEC61B Sec61 beta subunit -2.03475
MTIF2 mitochondrial translational initiation factor 2 -2.03465
ACSL3 acyl-CoA synthetase long-chain family member 3 -2.03373
ARHGAP15 Rho GTPase activating protein 15 -2.0324
GPC4 glypican 4 -2.02698
TM4SF4 transmembrane 4 L six family member 4 -2.02525
EXTL2 exostosin-like glycosyltransferase 2 -2.02395
GNG4 guanine nucleotide binding protein (G protein), gamma 4 -2.0232
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) -2.0212
COA3 cytochrome c oxidase assembly factor 3 -2.0187
MRPL15 mitochondrial ribosomal protein L15 -2.01765
EIF3L eukaryotic translation initiation factor 3, subunit L -2.01715
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -2.01515
SOBP sine oculis binding protein homolog (Drosophila) -2.0151
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -2.0144
RPS18 ribosomal protein S18 -2.012
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.0113
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 -2.00962
PLS3 plastin 3 -2.0094
SHPK sedoheptulokinase -2.0027