CRCGN012_HEPG2_24H:L14 Gene Set
Genes
38 genes differentially expressed following the CRCGN012_HEPG2_24H:L14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
9.62642
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.56256
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.34585
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.31628
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.27912
|
|
UBQLN2
|
ubiquilin 2
|
4.20246
|
|
PRR15L
|
proline rich 15-like
|
4.1922
|
|
STK10
|
serine/threonine kinase 10
|
4.14327
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.98445
|
|
CBR3
|
carbonyl reductase 3
|
3.8684
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
3.40052
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.81349
|
|
GRB10
|
growth factor receptor-bound protein 10
|
2.35041
|
|
REV1
|
REV1, polymerase (DNA directed)
|
2.27574
|
|
MRPL18
|
mitochondrial ribosomal protein L18
|
2.17652
|
|
MANBA
|
mannosidase, beta A, lysosomal
|
2.11457
|
|
STK26
|
serine/threonine protein kinase 26
|
2.07337
|
|
VAMP8
|
vesicle-associated membrane protein 8
|
2.03052
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-8.83495
|
|
CCNB2
|
cyclin B2
|
-7.17816
|
|
DNM1L
|
dynamin 1-like
|
-4.97716
|
|
VAT1
|
vesicle amine transport 1
|
-4.5571
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.52212
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-4.35398
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.25679
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.24464
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.1428
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.92081
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-3.82695
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.69211
|
|
GNAS
|
GNAS complex locus
|
-3.55058
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.32294
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.09377
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.85567
|
|
FANCF
|
Fanconi anemia, complementation group F
|
-2.20216
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.15836
|
|
USP6NL
|
USP6 N-terminal like
|
-2.15238
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.05714
|
