| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | safrole 10.05 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
52 genes differentially expressed following the CRCGN012_HEPG2_24H:L15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 7.55319 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 7.22801 |
| GSTZ1 | glutathione S-transferase zeta 1 | 6.70665 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.29383 |
| CHMP6 | charged multivesicular body protein 6 | 5.09469 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.8615 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.74339 |
| CHN1 | chimerin 1 | 4.60753 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.36619 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.1848 |
| NOSIP | nitric oxide synthase interacting protein | 3.42114 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.29998 |
| EAPP | E2F-associated phosphoprotein | 3.04446 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.94405 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.90796 |
| CYCS | cytochrome c, somatic | 2.79072 |
| EVL | Enah/Vasp-like | 2.60749 |
| EPN2 | epsin 2 | 2.52998 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.47912 |
| STK10 | serine/threonine kinase 10 | 2.47588 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 2.38319 |
| TBP | TATA box binding protein | 2.29316 |
| ATP11B | ATPase, class VI, type 11B | 2.27312 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.10264 |
| PTK2 | protein tyrosine kinase 2 | 2.0936 |
| REXO5 | RNA exonuclease 5 | 2.02297 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 2.01055 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB1 | cyclin B1 | -6.38538 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.4668 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -5.21752 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.10952 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.84817 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.77095 |
| LDHD | lactate dehydrogenase D | -4.49885 |
| VDAC1 | voltage-dependent anion channel 1 | -4.37422 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.0079 |
| DSG2 | desmoglein 2 | -3.45442 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.17875 |
| ACOT9 | acyl-CoA thioesterase 9 | -2.83415 |
| EGF | epidermal growth factor | -2.82307 |
| GDF15 | growth differentiation factor 15 | -2.57755 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.56765 |
| SESN1 | sestrin 1 | -2.5299 |
| CD320 | CD320 molecule | -2.51585 |
| VAT1 | vesicle amine transport 1 | -2.50086 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.4807 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.40427 |
| ADI1 | acireductone dioxygenase 1 | -2.25375 |
| GOLT1B | golgi transport 1B | -2.13976 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -2.1248 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.10483 |
| RECQL | RecQ helicase-like | -2.03223 |
