CRCGN012_HEPG2_24H:L17 Gene Set
Genes
48 genes differentially expressed following the CRCGN012_HEPG2_24H:L17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
7.121
|
|
CHN1
|
chimerin 1
|
5.68083
|
|
UBQLN2
|
ubiquilin 2
|
4.6513
|
|
MOK
|
MOK protein kinase
|
4.57756
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.53872
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.41623
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.17194
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.14701
|
|
STK10
|
serine/threonine kinase 10
|
3.74033
|
|
GATA3
|
GATA binding protein 3
|
3.49537
|
|
RPL39L
|
ribosomal protein L39-like
|
3.18744
|
|
GPATCH8
|
G patch domain containing 8
|
3.12097
|
|
LCN2
|
lipocalin 2
|
3.05525
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.85937
|
|
NMU
|
neuromedin U
|
2.73108
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.6255
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.60592
|
|
CSK
|
c-src tyrosine kinase
|
2.50902
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.32802
|
|
SAA2
|
serum amyloid A2
|
2.32273
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.2916
|
|
TPST1
|
tyrosylprotein sulfotransferase 1
|
2.15907
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
2.1572
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.11238
|
|
KIF20A
|
kinesin family member 20A
|
2.0169
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-7.72147
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-6.26724
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-5.97307
|
|
CCNB2
|
cyclin B2
|
-5.40628
|
|
ZNF586
|
zinc finger protein 586
|
-4.61381
|
|
PLK1
|
polo-like kinase 1
|
-4.48982
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.06348
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.79398
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.76456
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.42318
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.39666
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.37695
|
|
GDF15
|
growth differentiation factor 15
|
-2.93505
|
|
BLCAP
|
bladder cancer associated protein
|
-2.78544
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.61163
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.43417
|
|
TRAPPC6A
|
trafficking protein particle complex 6A
|
-2.41229
|
|
VPS35L
|
VPS35 endosomal protein sorting factor like
|
-2.3503
|
|
TMEM214
|
transmembrane protein 214
|
-2.24567
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.18998
|
|
MTFR1
|
mitochondrial fission regulator 1
|
-2.14481
|
|
MAP7
|
microtubule-associated protein 7
|
-2.12111
|
|
ZNF692
|
zinc finger protein 692
|
-2.00633
|
