CRCGN012_HEPG2_24H:L18 Gene Set
Genes
43 genes differentially expressed following the CRCGN012_HEPG2_24H:L18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
10.0
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
8.54897
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
7.51398
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
7.4532
|
|
LOC122526780
|
uncharacterized LOC122526780
|
5.69095
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
4.95701
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.71956
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.63539
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.58915
|
|
CSK
|
c-src tyrosine kinase
|
4.21324
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.51849
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.48006
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.1526
|
|
ZNF589
|
zinc finger protein 589
|
2.6652
|
|
SELENOT
|
selenoprotein T
|
2.55249
|
|
PCNA
|
proliferating cell nuclear antigen
|
2.45216
|
|
CHN1
|
chimerin 1
|
2.18111
|
|
HNRNPH1
|
heterogeneous nuclear ribonucleoprotein H1 (H)
|
2.16144
|
|
NCBP2
|
nuclear cap binding protein subunit 2, 20kDa
|
2.0953
|
|
DZANK1
|
double zinc ribbon and ankyrin repeat domains 1
|
2.05721
|
|
CDC42SE1
|
CDC42 small effector 1
|
2.01615
|
|
OSTF1
|
osteoclast stimulating factor 1
|
2.01268
|
|
GPATCH8
|
G patch domain containing 8
|
2.00352
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-9.96872
|
|
CCNB2
|
cyclin B2
|
-6.13336
|
|
LDHD
|
lactate dehydrogenase D
|
-5.11854
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.6529
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.53589
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.35243
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.2736
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-4.02525
|
|
TXNRD1
|
thioredoxin reductase 1
|
-3.09065
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.77563
|
|
EGF
|
epidermal growth factor
|
-2.53442
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.48062
|
|
GDF15
|
growth differentiation factor 15
|
-2.46036
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.36043
|
|
TOR1A
|
torsin family 1, member A (torsin A)
|
-2.24336
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.16409
|
|
MYH1
|
myosin, heavy chain 1, skeletal muscle, adult
|
-2.102
|
|
BCL2L14
|
BCL2-like 14 (apoptosis facilitator)
|
-2.09764
|
|
CCL15
|
chemokine (C-C motif) ligand 15
|
-2.08213
|
|
CDKN2B
|
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
|
-2.01964
|
