| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | urea 5.25 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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54 genes differentially expressed following the CRCGN012_HEPG2_24H:L22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CBR3 | carbonyl reductase 3 | 7.92735 |
| E2F2 | E2F transcription factor 2 | 4.86786 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.51384 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.4399 |
| RPL39L | ribosomal protein L39-like | 4.43527 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.25061 |
| UBQLN2 | ubiquilin 2 | 4.11587 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.89272 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.79695 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.76931 |
| TBC1D31 | TBC1 domain family, member 31 | 3.71914 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.70549 |
| GPATCH8 | G patch domain containing 8 | 3.06674 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.93828 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.90803 |
| GATA3 | GATA binding protein 3 | 2.87752 |
| SORBS3 | sorbin and SH3 domain containing 3 | 2.84615 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 2.81318 |
| EPHA3 | EPH receptor A3 | 2.72516 |
| PTPRC | protein tyrosine phosphatase, receptor type, C | 2.47308 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 2.47107 |
| MAP7 | microtubule-associated protein 7 | 2.45442 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.44177 |
| RAB31 | RAB31, member RAS oncogene family | 2.39655 |
| METRN | meteorin, glial cell differentiation regulator | 2.19447 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.07114 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.0056 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -8.87661 |
| ADI1 | acireductone dioxygenase 1 | -8.22587 |
| LDHD | lactate dehydrogenase D | -5.45154 |
| DSG2 | desmoglein 2 | -4.81272 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.27089 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -3.98937 |
| UBE3C | ubiquitin protein ligase E3C | -3.93683 |
| PDLIM1 | PDZ and LIM domain 1 | -3.23424 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -3.034 |
| GDF15 | growth differentiation factor 15 | -2.98154 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.91525 |
| ILK | integrin-linked kinase | -2.86243 |
| EGF | epidermal growth factor | -2.70631 |
| PDHX | pyruvate dehydrogenase complex, component X | -2.67895 |
| RNF167 | ring finger protein 167 | -2.54895 |
| PRPF4 | pre-mRNA processing factor 4 | -2.48139 |
| APIP | APAF1 interacting protein | -2.36608 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | -2.35493 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | -2.29105 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain | -2.23378 |
| GMPR | guanosine monophosphate reductase | -2.22775 |
| CCNB2 | cyclin B2 | -2.13579 |
| TXLNA | taxilin alpha | -2.10257 |
| WASHC4 | WASH complex subunit 4 | -2.06352 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -2.05258 |
| CAB39 | calcium binding protein 39 | -2.05064 |
| ZNF76 | zinc finger protein 76 | -2.00965 |
