CRCGN012_HEPG2_24H:L23 Gene Set
Genes
49 genes differentially expressed following the CRCGN012_HEPG2_24H:L23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
TAC4
|
tachykinin 4 (hemokinin)
|
3.94638
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
3.92096
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.90795
|
|
NOTCH1
|
notch 1
|
3.90636
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.47202
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.16044
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.09545
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.99087
|
|
CHN1
|
chimerin 1
|
2.82231
|
|
EPHA3
|
EPH receptor A3
|
2.44678
|
|
GATA3
|
GATA binding protein 3
|
2.41839
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.40995
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.35853
|
|
LCN2
|
lipocalin 2
|
2.32578
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.2901
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.26934
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.26779
|
|
FPGS
|
folylpolyglutamate synthase
|
2.19563
|
|
BAX
|
BCL2-associated X protein
|
2.17133
|
|
RB1
|
retinoblastoma 1
|
2.16525
|
|
PRKCH
|
protein kinase C, eta
|
2.15909
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.14291
|
|
FZD7
|
frizzled class receptor 7
|
2.10395
|
|
GPATCH8
|
G patch domain containing 8
|
2.09423
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-6.66955
|
|
CCNB2
|
cyclin B2
|
-4.63177
|
|
RPS5
|
ribosomal protein S5
|
-4.19032
|
|
LDHD
|
lactate dehydrogenase D
|
-3.81956
|
|
CDC20
|
cell division cycle 20
|
-3.81603
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.70907
|
|
MAP7
|
microtubule-associated protein 7
|
-3.31334
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-3.22036
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.07384
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.056
|
|
BLCAP
|
bladder cancer associated protein
|
-2.94063
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.84249
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.76025
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.69691
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.62099
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.40047
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.35599
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.34688
|
|
PPP2R5A
|
protein phosphatase 2, regulatory subunit B', alpha
|
-2.31862
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.24946
|
|
ETNK1
|
ethanolamine kinase 1
|
-2.18617
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.18246
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.17972
|
|
ZNF248
|
zinc finger protein 248
|
-2.17659
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.10053
|
