CRCGN012_HEPG2_24H:L24 Gene Set
Genes
40 genes differentially expressed following the CRCGN012_HEPG2_24H:L24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
5.06363
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.79563
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
4.57706
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.41507
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.19977
|
|
PFKL
|
phosphofructokinase, liver
|
3.8659
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.77161
|
|
STIMATE
|
STIM activating enhancer
|
3.68402
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.65732
|
|
PRR15L
|
proline rich 15-like
|
3.17113
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
2.99191
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.98126
|
|
TLR4
|
toll-like receptor 4
|
2.84519
|
|
NUCB2
|
nucleobindin 2
|
2.72095
|
|
EIF2S3
|
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
|
2.69263
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.63028
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.45484
|
|
SUCLG2
|
succinate-CoA ligase, GDP-forming, beta subunit
|
2.37891
|
|
JADE2
|
jade family PHD finger 2
|
2.36188
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.28572
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.22525
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.17391
|
|
GPX4
|
glutathione peroxidase 4
|
2.16533
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.13476
|
|
TIPRL
|
TOR signaling pathway regulator
|
2.11379
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.0287
|
|
ZNF253
|
zinc finger protein 253
|
2.0246
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-8.78953
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-5.34657
|
|
LDHD
|
lactate dehydrogenase D
|
-4.8518
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.65899
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.56806
|
|
CDC25B
|
cell division cycle 25B
|
-3.22208
|
|
CANT1
|
calcium activated nucleotidase 1
|
-2.65035
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
-2.6308
|
|
EGF
|
epidermal growth factor
|
-2.59002
|
|
IPO13
|
importin 13
|
-2.51072
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.18907
|
|
PRSS22
|
protease, serine, 22
|
-2.14162
|
|
PTPN13
|
protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
|
-2.11892
|
