CRCGN012_HEPG2_24H:M01 Gene Set
Genes
48 genes differentially expressed following the CRCGN012_HEPG2_24H:M01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CCL2
|
chemokine (C-C motif) ligand 2
|
5.39793
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
5.00443
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
4.17266
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.04959
|
|
STK10
|
serine/threonine kinase 10
|
3.9085
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.89225
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.5974
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.53549
|
|
NOTCH1
|
notch 1
|
3.43112
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.16761
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.78581
|
|
SLC75A1
|
solute carrier family 75 member 1
|
2.72278
|
|
MOK
|
MOK protein kinase
|
2.66077
|
|
GPATCH8
|
G patch domain containing 8
|
2.53833
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.49001
|
|
KLHL9
|
kelch-like family member 9
|
2.48329
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.4561
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.35665
|
|
TLR4
|
toll-like receptor 4
|
2.34598
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.32067
|
|
LCN2
|
lipocalin 2
|
2.2976
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.21453
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.18366
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.18341
|
|
LEP
|
leptin
|
2.15298
|
|
TNMD
|
tenomodulin
|
2.13427
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.1238
|
|
SATB1
|
SATB homeobox 1
|
2.0275
|
|
CHN1
|
chimerin 1
|
2.02122
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-7.98019
|
|
ADI1
|
acireductone dioxygenase 1
|
-7.38318
|
|
CCNB2
|
cyclin B2
|
-7.21786
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.59308
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-4.16171
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.13857
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.9431
|
|
CDC20
|
cell division cycle 20
|
-3.93445
|
|
FBXO7
|
F-box protein 7
|
-3.37067
|
|
GDF15
|
growth differentiation factor 15
|
-2.90065
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.8174
|
|
RNF167
|
ring finger protein 167
|
-2.5264
|
|
GNAS
|
GNAS complex locus
|
-2.48255
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.46702
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.39851
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.21132
|
|
USP6NL
|
USP6 N-terminal like
|
-2.17055
|
|
PTK7
|
protein tyrosine kinase 7 (inactive)
|
-2.07976
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-2.06216
|
