CRCGN012_HEPG2_24H:M02 Gene Set
Genes
42 genes differentially expressed following the CRCGN012_HEPG2_24H:M02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
7.14494
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.99279
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.02935
|
|
ZNF589
|
zinc finger protein 589
|
3.99441
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.38644
|
|
CHN1
|
chimerin 1
|
3.32187
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.00937
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.92664
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.87185
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.85927
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.82741
|
|
CDC45
|
cell division cycle 45
|
2.65948
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.51462
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.44973
|
|
CTSL
|
cathepsin L
|
2.28194
|
|
SATB1
|
SATB homeobox 1
|
2.09038
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-7.61327
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.57351
|
|
CDC20
|
cell division cycle 20
|
-5.07201
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-5.03124
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.46553
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.22606
|
|
EGF
|
epidermal growth factor
|
-4.1614
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.28377
|
|
CDC25B
|
cell division cycle 25B
|
-3.18425
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.17713
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.12392
|
|
LYPLA1
|
lysophospholipase I
|
-3.02416
|
|
CCNB1
|
cyclin B1
|
-2.94677
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.89112
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.88917
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.81523
|
|
ZNF586
|
zinc finger protein 586
|
-2.75406
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.61674
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.49725
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.44596
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.3196
|
|
EXT1
|
exostosin glycosyltransferase 1
|
-2.30895
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.24034
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.19955
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.16858
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.03669
|
