CRCGN012_HEPG2_24H:M03 Gene Set
Genes
51 genes differentially expressed following the CRCGN012_HEPG2_24H:M03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
6.27704
|
|
STAP2
|
signal transducing adaptor family member 2
|
5.60097
|
|
CSK
|
c-src tyrosine kinase
|
4.81046
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.359
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.34664
|
|
PRR15L
|
proline rich 15-like
|
4.14441
|
|
CYCS
|
cytochrome c, somatic
|
3.97172
|
|
UBQLN2
|
ubiquilin 2
|
3.93597
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.90686
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.887
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.62989
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.41367
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.38646
|
|
PCDHB11
|
protocadherin beta 11
|
3.26043
|
|
CBR3
|
carbonyl reductase 3
|
3.1564
|
|
TXNL4B
|
thioredoxin-like 4B
|
3.09151
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.80444
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.79485
|
|
EPHA3
|
EPH receptor A3
|
2.64002
|
|
KIF14
|
kinesin family member 14
|
2.36704
|
|
VGLL4
|
vestigial-like family member 4
|
2.32151
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.2613
|
|
SH3D19
|
SH3 domain containing 19
|
2.16493
|
|
JADE2
|
jade family PHD finger 2
|
2.15277
|
|
NPTXR
|
neuronal pentraxin receptor
|
2.06644
|
|
UBA3
|
ubiquitin-like modifier activating enzyme 3
|
2.00583
|
|
RPL34
|
ribosomal protein L34
|
2.00222
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TUBB6
|
tubulin, beta 6 class V
|
-4.49616
|
|
TCTN1
|
tectonic family member 1
|
-4.38596
|
|
VAT1
|
vesicle amine transport 1
|
-4.32156
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.28439
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.20124
|
|
THAP11
|
THAP domain containing 11
|
-4.11914
|
|
ZNF586
|
zinc finger protein 586
|
-4.02961
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-4.02404
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.9434
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.85068
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.78477
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.64632
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-3.46659
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.43186
|
|
SPAG4
|
sperm associated antigen 4
|
-3.1849
|
|
CCNB2
|
cyclin B2
|
-3.10392
|
|
NVL
|
nuclear VCP-like
|
-2.78748
|
|
TMEM11
|
transmembrane protein 11
|
-2.65123
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.34129
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.30048
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.24667
|
|
REC8
|
REC8 meiotic recombination protein
|
-2.22513
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.14851
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
-2.09973
|
