CRCGN012_HEPG2_24H:M05 Gene Set
Genes
38 genes differentially expressed following the CRCGN012_HEPG2_24H:M05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
6.43601
|
|
CSK
|
c-src tyrosine kinase
|
5.59633
|
|
CCNF
|
cyclin F
|
4.78265
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.66551
|
|
LCN2
|
lipocalin 2
|
3.56236
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.51516
|
|
CCNA1
|
cyclin A1
|
3.27354
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.14704
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.13334
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.13141
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.06647
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.97866
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.87687
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
2.80634
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.46575
|
|
EPN2
|
epsin 2
|
2.45456
|
|
MOK
|
MOK protein kinase
|
2.43978
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
2.40597
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.2215
|
|
HEBP1
|
heme binding protein 1
|
2.14848
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.10824
|
|
EPHA3
|
EPH receptor A3
|
2.03113
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-6.61884
|
|
ADI1
|
acireductone dioxygenase 1
|
-6.31429
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-4.20722
|
|
VAT1
|
vesicle amine transport 1
|
-3.92086
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.54318
|
|
CAB39
|
calcium binding protein 39
|
-3.33148
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-3.13486
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.1285
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.02186
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.88644
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.84656
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.71238
|
|
GDF15
|
growth differentiation factor 15
|
-2.61239
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.49761
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.3917
|
|
CCNB1
|
cyclin B1
|
-2.28495
|
