CRCGN012_HEPG2_24H:M06 Gene Set
Genes
46 genes differentially expressed following the CRCGN012_HEPG2_24H:M06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
8.03592
|
|
UBQLN2
|
ubiquilin 2
|
4.6736
|
|
SQOR
|
sulfide quinone oxidoreductase
|
4.28667
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
4.06898
|
|
PRR15L
|
proline rich 15-like
|
4.04043
|
|
MYBL2
|
v-myb avian myeloblastosis viral oncogene homolog-like 2
|
3.95919
|
|
NOTCH1
|
notch 1
|
3.84704
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.81117
|
|
VGLL4
|
vestigial-like family member 4
|
3.77226
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.47129
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.38931
|
|
TATDN2
|
TatD DNase domain containing 2
|
3.16308
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.58231
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.36997
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.33268
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.32315
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.30285
|
|
CHN1
|
chimerin 1
|
2.21409
|
|
KIF14
|
kinesin family member 14
|
2.19422
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.14057
|
|
ECH1
|
enoyl CoA hydratase 1, peroxisomal
|
2.0719
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.05723
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
DNM1L
|
dynamin 1-like
|
-4.81342
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.21182
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.89191
|
|
ZNF586
|
zinc finger protein 586
|
-3.81099
|
|
EGF
|
epidermal growth factor
|
-3.78389
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.74006
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.67799
|
|
CDC20
|
cell division cycle 20
|
-3.36458
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-3.22146
|
|
CD58
|
CD58 molecule
|
-3.06379
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-3.02647
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.82473
|
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
-2.69951
|
|
DSG2
|
desmoglein 2
|
-2.39283
|
|
HMOX1
|
heme oxygenase 1
|
-2.35809
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.30688
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.29459
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.14748
|
|
RINT1
|
RAD50 interactor 1
|
-2.12313
|
|
RNFT1-DT
|
RNFT1 divergent transcript
|
-2.10782
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.07788
|
|
RPAP3
|
RNA polymerase II associated protein 3
|
-2.03132
|
|
PDIA5
|
protein disulfide isomerase family A, member 5
|
-2.01098
|
