CRCGN012_HEPG2_24H:M08 Gene Set
Genes
42 genes differentially expressed following the CRCGN012_HEPG2_24H:M08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
8.95565
|
|
CHN1
|
chimerin 1
|
5.62658
|
|
STK10
|
serine/threonine kinase 10
|
4.4758
|
|
NOTCH1
|
notch 1
|
4.4482
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.40163
|
|
MYLK
|
myosin light chain kinase
|
4.39147
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.26318
|
|
MCOLN1
|
mucolipin 1
|
4.0675
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.02372
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.5369
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.4238
|
|
FCHO1
|
FCH domain only 1
|
3.30135
|
|
CYCS
|
cytochrome c, somatic
|
3.1668
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.14841
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.99831
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.52813
|
|
HEBP1
|
heme binding protein 1
|
2.43766
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.33952
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.21425
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.04901
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLCD3A
|
TLC domain containing 3A
|
-6.03987
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.32355
|
|
CDC20
|
cell division cycle 20
|
-4.26765
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.25611
|
|
GOLT1B
|
golgi transport 1B
|
-4.21077
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.07394
|
|
LDHD
|
lactate dehydrogenase D
|
-3.83594
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.72665
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.32939
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.21725
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.95942
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.7092
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.66621
|
|
USP6NL
|
USP6 N-terminal like
|
-2.58652
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.55317
|
|
MYC
|
v-myc avian myelocytomatosis viral oncogene homolog
|
-2.54012
|
|
PSMB10
|
proteasome (prosome, macropain) subunit, beta type, 10
|
-2.48887
|
|
RNF167
|
ring finger protein 167
|
-2.47683
|
|
MCUB
|
mitochondrial calcium uniporter dominant negative subunit beta
|
-2.30766
|
|
CD58
|
CD58 molecule
|
-2.27182
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.10292
|
|
KIAA1614
|
KIAA1614
|
-2.02622
|
