| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | chloroform 4.97 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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79 genes differentially expressed following the CRCGN012_HEPG2_24H:M10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 7.26128 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 7.10718 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 7.00621 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 6.99815 |
| NOTCH1 | notch 1 | 6.25811 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.83706 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.22354 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.3685 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.99166 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.93464 |
| ABHD6 | abhydrolase domain containing 6 | 2.84485 |
| E2F2 | E2F transcription factor 2 | 2.80095 |
| LOC122526780 | uncharacterized LOC122526780 | 2.76239 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.69686 |
| BZW2 | basic leucine zipper and W2 domains 2 | 2.67384 |
| ABCC8 | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 | 2.49007 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 2.47184 |
| TAC4 | tachykinin 4 (hemokinin) | 2.40301 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.38342 |
| KLHL21 | kelch-like family member 21 | 2.34915 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.32067 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.30958 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.24857 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.23606 |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 | 2.19282 |
| GPATCH8 | G patch domain containing 8 | 2.17149 |
| CORO2A | coronin, actin binding protein, 2A | 2.16169 |
| FAM53C | family with sequence similarity 53, member C | 2.14743 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 2.12758 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 2.11461 |
| RASA4B | RAS p21 protein activator 4B | 2.08787 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.08498 |
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 | 2.0778 |
| STXBP2 | syntaxin binding protein 2 | 2.07076 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.06169 |
| NUBP2 | nucleotide binding protein 2 | 2.05985 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.05529 |
| HYOU1 | hypoxia up-regulated 1 | 2.0222 |
| KYAT1 | kynurenine aminotransferase 1 | 2.00867 |
| Symbol | Name | Standardized Value |
|---|---|---|
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -7.22053 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -7.20818 |
| CDC20 | cell division cycle 20 | -6.6843 |
| CCNB2 | cyclin B2 | -6.3561 |
| LDHD | lactate dehydrogenase D | -5.30224 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -5.01639 |
| WASHC4 | WASH complex subunit 4 | -5.01139 |
| HSPB1 | heat shock 27kDa protein 1 | -4.39443 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.38216 |
| GOLT1B | golgi transport 1B | -4.31038 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.98389 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -3.66575 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -3.43 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.25131 |
| TBCB | tubulin folding cofactor B | -3.19782 |
| DNM1L | dynamin 1-like | -3.15072 |
| GNAS | GNAS complex locus | -3.12151 |
| CAPNS1 | calpain, small subunit 1 | -3.08956 |
| VDAC1 | voltage-dependent anion channel 1 | -2.87373 |
| THAP11 | THAP domain containing 11 | -2.87076 |
| RBM42 | RNA binding motif protein 42 | -2.85911 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.70809 |
| ZNF146 | zinc finger protein 146 | -2.5024 |
| PSENEN | presenilin enhancer gamma secretase subunit | -2.50164 |
| TMEM147 | transmembrane protein 147 | -2.48896 |
| LIN37 | lin-37 DREAM MuvB core complex component | -2.41568 |
| VPS4A | vacuolar protein sorting 4 homolog A (S. cerevisiae) | -2.36159 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -2.31788 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -2.30024 |
| RGS2 | regulator of G-protein signaling 2 | -2.25663 |
| TMEM184C | transmembrane protein 184C | -2.2489 |
| CSNK2B | casein kinase 2, beta polypeptide | -2.22859 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | -2.20118 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | -2.12665 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -2.10169 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.09312 |
| EIF2B2 | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa | -2.09267 |
| ACTN4 | actinin, alpha 4 | -2.04446 |
| TUBA3C | tubulin, alpha 3c | -2.01462 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | -2.0026 |
