| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | chloroform 2.49 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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86 genes differentially expressed following the CRCGN012_HEPG2_24H:M11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPP38 | ribonuclease P/MRP 38kDa subunit | 7.46768 |
| UBQLN2 | ubiquilin 2 | 6.70901 |
| E2F2 | E2F transcription factor 2 | 6.60652 |
| PRR15L | proline rich 15-like | 6.09562 |
| CCDC85B | coiled-coil domain containing 85B | 5.22547 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 4.83354 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.59247 |
| LCN2 | lipocalin 2 | 4.28126 |
| DENND2D | DENN/MADD domain containing 2D | 4.27711 |
| MCOLN1 | mucolipin 1 | 4.15082 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.14985 |
| ADRB2 | adrenoceptor beta 2, surface | 3.82172 |
| MOK | MOK protein kinase | 3.29588 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.25152 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.18344 |
| CSK | c-src tyrosine kinase | 3.11705 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.06232 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 3.04629 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.85722 |
| NOSIP | nitric oxide synthase interacting protein | 2.82504 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.75685 |
| NPY5R | neuropeptide Y receptor Y5 | 2.67001 |
| KCND1 | potassium channel, voltage gated Shal related subfamily D, member 1 | 2.63368 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 2.6008 |
| BAX | BCL2-associated X protein | 2.48553 |
| CCNF | cyclin F | 2.3633 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.34616 |
| PGP | phosphoglycolate phosphatase | 2.32158 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.31566 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.28007 |
| PRPF18 | pre-mRNA processing factor 18 | 2.26904 |
| TLR4 | toll-like receptor 4 | 2.21411 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 2.18489 |
| STIMATE | STIM activating enhancer | 2.17388 |
| VAV1 | vav 1 guanine nucleotide exchange factor | 2.16927 |
| TTI2 | TELO2 interacting protein 2 | 2.15907 |
| AKAP3 | A kinase (PRKA) anchor protein 3 | 2.15328 |
| EVL | Enah/Vasp-like | 2.13657 |
| JADE2 | jade family PHD finger 2 | 2.13439 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.12619 |
| SIGLEC9 | sialic acid binding Ig-like lectin 9 | 2.11262 |
| CRTAP | cartilage associated protein | 2.0992 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.08656 |
| RIOX1 | ribosomal oxygenase 1 | 2.06706 |
| MYLK | myosin light chain kinase | 2.04609 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 2.03629 |
| TNIP3 | TNFAIP3 interacting protein 3 | 2.0102 |
| LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 | 2.00141 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNM1L | dynamin 1-like | -7.45333 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.67219 |
| UGDH | UDP-glucose 6-dehydrogenase | -4.75121 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.73815 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.65026 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.3821 |
| HAT1 | histone acetyltransferase 1 | -4.36888 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.27139 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -4.12775 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -3.91983 |
| ADI1 | acireductone dioxygenase 1 | -3.794 |
| ANKRD10 | ankyrin repeat domain 10 | -3.45054 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.21444 |
| PCNA | proliferating cell nuclear antigen | -3.14226 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -3.10249 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.02028 |
| TRAPPC3 | trafficking protein particle complex 3 | -2.95802 |
| RHEB | Ras homolog enriched in brain | -2.8369 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.83458 |
| VAT1 | vesicle amine transport 1 | -2.6305 |
| CUL1 | cullin 1 | -2.62998 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.62607 |
| ENOPH1 | enolase-phosphatase 1 | -2.62307 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -2.57816 |
| NVL | nuclear VCP-like | -2.45101 |
| GNAS | GNAS complex locus | -2.42844 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.28509 |
| BCS1L | BC1 (ubiquinol-cytochrome c reductase) synthesis-like | -2.23418 |
| WDR12 | WD repeat domain 12 | -2.21576 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -2.20906 |
| MACF1 | microtubule-actin crosslinking factor 1 | -2.15492 |
| PPOX | protoporphyrinogen oxidase | -2.11032 |
| TCTN1 | tectonic family member 1 | -2.09902 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -2.08859 |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | -2.05832 |
| MTX2 | metaxin 2 | -2.01903 |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa | -2.00435 |
| AKIRIN1 | akirin 1 | -2.00305 |
