CRCGN012_HEPG2_24H:M14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,2',5,5'-tetrachlorobenzidine 20.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

392 genes differentially expressed following the CRCGN012_HEPG2_24H:M14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MVP major vault protein 8.012
TIMP2 TIMP metallopeptidase inhibitor 2 7.99437
NANOS3 nanos homolog 3 (Drosophila) 7.80196
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 7.18171
CDPF1 cysteine-rich, DPF motif domain containing 1 6.95125
SQOR sulfide quinone oxidoreductase 6.51328
LCN2 lipocalin 2 6.36624
NOTCH1 notch 1 6.28648
VAT1 vesicle amine transport 1 6.13202
DSG2 desmoglein 2 6.01473
FOSL1 FOS-like antigen 1 5.98927
ACOT9 acyl-CoA thioesterase 9 5.78228
STX1A syntaxin 1A (brain) 5.57431
TUBB6 tubulin, beta 6 class V 5.317
CXCR4 chemokine (C-X-C motif) receptor 4 4.896
CNPY3 canopy FGF signaling regulator 3 4.43464
PNKP polynucleotide kinase 3'-phosphatase 4.3845
EPN2 epsin 2 4.28677
KIFBP kinesin family binding protein 4.22264
RALB v-ral simian leukemia viral oncogene homolog B 4.19285
CAB39 calcium binding protein 39 4.11581
GPER1 G protein-coupled estrogen receptor 1 4.03822
PRKCQ protein kinase C, theta 4.02787
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 3.9677
TBPL1 TBP-like 1 3.89327
JADE2 jade family PHD finger 2 3.85655
STK10 serine/threonine kinase 10 3.81485
LRP10 low density lipoprotein receptor-related protein 10 3.81128
GPATCH8 G patch domain containing 8 3.7693
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.76921
INPP1 inositol polyphosphate-1-phosphatase 3.76714
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 3.69338
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 3.6926
CIAO3 cytosolic iron-sulfur assembly component 3 3.65373
SOCS2 suppressor of cytokine signaling 2 3.60289
TXNRD1 thioredoxin reductase 1 3.47439
S100A4 S100 calcium binding protein A4 3.42816
KLHL21 kelch-like family member 21 3.42632
CFLAR CASP8 and FADD-like apoptosis regulator 3.36303
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 3.34495
MICALL1 MICAL-like 1 3.33175
E2F2 E2F transcription factor 2 3.32926
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.31361
SQSTM1 sequestosome 1 3.28546
TOMM34 translocase of outer mitochondrial membrane 34 3.27795
PROCR protein C receptor, endothelial 3.22777
S100A13 S100 calcium binding protein A13 3.21071
ZNF586 zinc finger protein 586 3.20609
SOX4 SRY (sex determining region Y)-box 4 3.20356
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.19622
DYNLT3 dynein, light chain, Tctex-type 3 3.19297
VGLL4 vestigial-like family member 4 3.18248
COG7 component of oligomeric golgi complex 7 3.11914
EPHB2 EPH receptor B2 3.10941
TMEM50A transmembrane protein 50A 3.09266
ZFP36 ZFP36 ring finger protein 3.0692
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 3.05908
NOSIP nitric oxide synthase interacting protein 3.04541
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 3.03109
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.02166
DHRS7 dehydrogenase/reductase (SDR family) member 7 3.01473
GATA3 GATA binding protein 3 2.98611
TP53I3 tumor protein p53 inducible protein 3 2.94257
H2BC12 H2B clustered histone 12 2.9329
AHNAK2 AHNAK nucleoprotein 2 2.92808
IER3 immediate early response 3 2.9266
CLTB clathrin, light chain B 2.8288
CHMP6 charged multivesicular body protein 6 2.81829
FPGS folylpolyglutamate synthase 2.81785
LSR lipolysis stimulated lipoprotein receptor 2.81553
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.80683
SMTN smoothelin 2.74352
SLC35F6 solute carrier family 35, member F6 2.73573
GRB10 growth factor receptor-bound protein 10 2.72652
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.692
MMRN2 multimerin 2 2.68928
TPD52L2 tumor protein D52-like 2 2.65934
PELI1 pellino E3 ubiquitin protein ligase 1 2.65491
STX4 syntaxin 4 2.643
BYSL bystin-like 2.64215
HTRA1 HtrA serine peptidase 1 2.63232
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 2.62446
CSK c-src tyrosine kinase 2.61652
CDA cytidine deaminase 2.6153
NCK2 NCK adaptor protein 2 2.60853
CYB561 cytochrome b561 2.59673
UBE2L6 ubiquitin-conjugating enzyme E2L 6 2.59608
MAP7D1 MAP7 domain containing 1 2.57977
HOXA10 homeobox A10 2.56917
NPC1 Niemann-Pick disease, type C1 2.56684
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.55078
IL4R interleukin 4 receptor 2.54876
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 2.54522
MAD2L1BP MAD2L1 binding protein 2.54189
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 2.52233
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.51461
EAPP E2F-associated phosphoprotein 2.50837
MEAK7 MTOR associated protein, eak-7 homolog 2.46723
MAP1S microtubule-associated protein 1S 2.46261
FASTKD5 FAST kinase domains 5 2.46005
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.45821
CSNK1E casein kinase 1, epsilon 2.44825
IGF2R insulin-like growth factor 2 receptor 2.43619
GADD45A growth arrest and DNA-damage-inducible, alpha 2.43387
SMIM40 small integral membrane protein 40 2.43281
STXBP2 syntaxin binding protein 2 2.43123
H2BC21 H2B clustered histone 21 2.41916
CTTN cortactin 2.41119
NIPSNAP2 nipsnap homolog 2 2.40767
FLNC filamin C, gamma 2.40597
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.39971
TES testin LIM domain protein 2.39909
ARID4B AT rich interactive domain 4B (RBP1-like) 2.3737
KDR kinase insert domain receptor 2.36726
PORCN porcupine homolog (Drosophila) 2.36685
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.35199
MAPK13 mitogen-activated protein kinase 13 2.33613
SFXN3 sideroflexin 3 2.33429
PODXL2 podocalyxin-like 2 2.33374
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 2.3277
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 2.29759
MAB21L2 mab-21-like 2 (C. elegans) 2.2915
SH2B3 SH2B adaptor protein 3 2.28461
NCF2 neutrophil cytosolic factor 2 2.28006
EMCN endomucin 2.27937
LAMC2 laminin, gamma 2 2.26737
TICAM1 toll-like receptor adaptor molecule 1 2.25358
NELFE negative elongation factor complex member E 2.25091
FABP2 fatty acid binding protein 2, intestinal 2.24757
TRIB1 tribbles pseudokinase 1 2.22995
GABPB1 GA binding protein transcription factor, beta subunit 1 2.22601
PXDC1 PX domain containing 1 2.22008
BPHL biphenyl hydrolase-like (serine hydrolase) 2.20657
RGS5 regulator of G-protein signaling 5 2.20615
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 2.19676
BAD BCL2-associated agonist of cell death 2.19493
MYH15 myosin, heavy chain 15 2.1836
FAAP20 FA core complex associated protein 20 2.18313
MON1B MON1 secretory trafficking family member B 2.17682
KLHL36 kelch-like family member 36 2.17479
ANGPT2 angiopoietin 2 2.17301
DBN1 drebrin 1 2.16851
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.16348
AP1B1 adaptor-related protein complex 1, beta 1 subunit 2.15733
IFT57 intraflagellar transport 57 2.152
NACAD NAC alpha domain containing 2.15123
ADGRE5 adhesion G protein-coupled receptor E5 2.14635
TRIP4 thyroid hormone receptor interactor 4 2.13589
ZNF362 zinc finger protein 362 2.13089
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 2.12921
SOX17 SRY (sex determining region Y)-box 17 2.12679
MYH9 myosin, heavy chain 9, non-muscle 2.12627
SLC35F2 solute carrier family 35, member F2 2.12578
TUBAL3 tubulin, alpha-like 3 2.12347
EPS8L3 EPS8-like 3 2.1233
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.12293
MEGF8 multiple EGF-like-domains 8 2.11363
CYTH2 cytohesin 2 2.1128
MMP26 matrix metallopeptidase 26 2.09545
CRX cone-rod homeobox 2.08919
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 2.08898
PHOX2A paired-like homeobox 2a 2.08279
RGL2 ral guanine nucleotide dissociation stimulator-like 2 2.08106
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 2.0777
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 2.0765
KLF7 Kruppel-like factor 7 (ubiquitous) 2.07218
DOCK6 dedicator of cytokinesis 6 2.06909
KIAA0408 KIAA0408 2.0687
RBKS ribokinase 2.06075
TMEM156 transmembrane protein 156 2.05926
DIPK1A divergent protein kinase domain 1A 2.05884
S1PR1 sphingosine-1-phosphate receptor 1 2.0542
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.0503
PLEK2 pleckstrin 2 2.04991
MTCH1 mitochondrial carrier 1 2.04684
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.0466
RAB9A RAB9A, member RAS oncogene family 2.04543
MCOLN1 mucolipin 1 2.04293
EFNA2 ephrin-A2 2.04166
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 2.03732
CORO1A coronin, actin binding protein, 1A 2.03689
FRMD4B FERM domain containing 4B 2.03572
MEST mesoderm specific transcript 2.03182
SLC38A12 solute carrier family 38 member 12 2.02122
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G 2.01804
TP53BP1 tumor protein p53 binding protein 1 2.01762
CBARP CACN subunit beta associated regulatory protein 2.01661
EBNA1BP2 EBNA1 binding protein 2 2.01405
PRKCD protein kinase C, delta 2.00519
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 2.0033
AARSD1 alanyl-tRNA synthetase domain containing 1 2.00311
DEF8 differentially expressed in FDCP 8 homolog (mouse) 2.00277
TRIM39-RPP21 TRIM39-RPP21 readthrough 2.00145
AHDC1 AT hook, DNA binding motif, containing 1 2.00129

decreased expression

Symbol Name Standardized Value
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -8.43999
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -7.42649
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -7.02576
B4GAT1 beta-1,4-glucuronyltransferase 1 -6.86109
FGFR4 fibroblast growth factor receptor 4 -6.77185
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -6.56664
PGM1 phosphoglucomutase 1 -6.43825
PEG10 paternally expressed 10 -5.76394
PECR peroxisomal trans-2-enoyl-CoA reductase -5.47092
CDK1 cyclin-dependent kinase 1 -5.15036
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -5.05822
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -5.02615
TBC1D10C TBC1 domain family, member 10C -5.02499
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -4.78879
KLHDC2 kelch domain containing 2 -4.72295
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -4.59948
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -4.59684
HMGA2 high mobility group AT-hook 2 -4.50451
ADI1 acireductone dioxygenase 1 -4.44579
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.41605
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -4.24226
BLCAP bladder cancer associated protein -4.23022
TOP2A topoisomerase (DNA) II alpha 170kDa -4.18713
CHEK2 checkpoint kinase 2 -4.1853
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -4.14618
MELK maternal embryonic leucine zipper kinase -4.05696
TOR1A torsin family 1, member A (torsin A) -3.99276
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.91603
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.86457
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -3.7886
HADH hydroxyacyl-CoA dehydrogenase -3.75657
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -3.73168
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.66666
CCNA2 cyclin A2 -3.60774
PRPF4 pre-mRNA processing factor 4 -3.57682
GOLT1B golgi transport 1B -3.47598
GLOD4 glyoxalase domain containing 4 -3.44872
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.40299
CRELD2 cysteine-rich with EGF-like domains 2 -3.38796
PRUNE1 prune exopolyphosphatase 1 -3.34365
UGDH UDP-glucose 6-dehydrogenase -3.33032
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.32954
BLMH bleomycin hydrolase -3.26124
AMBP alpha-1-microglobulin/bikunin precursor -3.20667
TSEN2 TSEN2 tRNA splicing endonuclease subunit -3.18015
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.16553
ALG6 ALG6, alpha-1,3-glucosyltransferase -3.1655
ERBB2 erb-b2 receptor tyrosine kinase 2 -3.16246
LDHD lactate dehydrogenase D -3.15276
SLC35H1 solute carrier family 35 member H1 -3.14993
MLEC malectin -3.14552
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.12452
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -3.11928
TOMM70 translocase of outer mitochondrial membrane 70 -3.10878
NCAPD2 non-SMC condensin I complex, subunit D2 -3.08571
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -3.08171
AURKB aurora kinase B -3.07464
UBE2C ubiquitin-conjugating enzyme E2C -3.05815
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.03595
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -3.0273
PARP1 poly (ADP-ribose) polymerase 1 -3.0188
C2CD5 C2 calcium-dependent domain containing 5 -3.01097
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -2.98932
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.94833
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.92901
USP6NL USP6 N-terminal like -2.90772
TCTN1 tectonic family member 1 -2.90557
CDC6 cell division cycle 6 -2.87705
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.87536
RFC2 replication factor C (activator 1) 2, 40kDa -2.87217
ZDHHC6 zinc finger, DHHC-type containing 6 -2.86352
DHRS2 dehydrogenase/reductase (SDR family) member 2 -2.86264
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.85856
HMOX1 heme oxygenase 1 -2.83998
MAT1A methionine adenosyltransferase I, alpha -2.82797
RMI1 RecQ mediated genome instability 1 -2.81747
STAT1 signal transducer and activator of transcription 1, 91kDa -2.76091
ACAA1 acetyl-CoA acyltransferase 1 -2.72868
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.71457
NIPSNAP1 nipsnap homolog 1 (C. elegans) -2.71069
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -2.68252
PSRC1 proline/serine-rich coiled-coil 1 -2.67284
ETFB electron-transfer-flavoprotein, beta polypeptide -2.67008
ICAM3 intercellular adhesion molecule 3 -2.66937
UBXN8 UBX domain protein 8 -2.64357
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.62855
GMCL1 germ cell-less, spermatogenesis associated 1 -2.6128
PHGDH phosphoglycerate dehydrogenase -2.59648
NFIL3 nuclear factor, interleukin 3 regulated -2.577
PCCB propionyl CoA carboxylase, beta polypeptide -2.5768
MBL2 mannose-binding lectin (protein C) 2, soluble -2.56515
POLR1A polymerase (RNA) I polypeptide A, 194kDa -2.56144
ZW10 zw10 kinetochore protein -2.55542
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -2.54675
SMCO4 single-pass membrane protein with coiled-coil domains 4 -2.54515
KDM3A lysine (K)-specific demethylase 3A -2.52218
WASHC4 WASH complex subunit 4 -2.5108
RTRAF RNA transcription, translation and transport factor -2.50838
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.49081
AGMAT agmatine ureohydrolase (agmatinase) -2.48539
ASF1B anti-silencing function 1B histone chaperone -2.48222
DBF4 DBF4 zinc finger -2.46597
POLR1G RNA polymerase I subunit G -2.45575
ERBB3 erb-b2 receptor tyrosine kinase 3 -2.45529
TMEM97 transmembrane protein 97 -2.45083
GAMT guanidinoacetate N-methyltransferase -2.45014
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.44464
AHSG alpha-2-HS-glycoprotein -2.42067
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -2.42026
UXT ubiquitously-expressed, prefoldin-like chaperone -2.41237
TMX1 thioredoxin-related transmembrane protein 1 -2.40713
PPIF peptidylprolyl isomerase F -2.38818
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.38175
EML4 echinoderm microtubule associated protein like 4 -2.38034
MBNL3 muscleblind-like splicing regulator 3 -2.37921
SIGLEC15 sialic acid binding Ig-like lectin 15 -2.37739
DHFR dihydrofolate reductase -2.37167
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -2.36516
FGL1 fibrinogen-like 1 -2.36166
PIPOX pipecolic acid oxidase -2.35163
CDK6 cyclin-dependent kinase 6 -2.34732
BRIX1 BRX1, biogenesis of ribosomes -2.34635
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.34567
AK4 adenylate kinase 4 -2.33201
ASGR1 asialoglycoprotein receptor 1 -2.32731
CD320 CD320 molecule -2.32531
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.32285
TERT telomerase reverse transcriptase -2.31228
APOM apolipoprotein M -2.30693
CCDC85B coiled-coil domain containing 85B -2.30157
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.29649
CPB2 carboxypeptidase B2 (plasma) -2.29513
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -2.28072
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.2704
MSH6 mutS homolog 6 -2.26968
NXT2 nuclear transport factor 2-like export factor 2 -2.26961
APOH apolipoprotein H (beta-2-glycoprotein I) -2.26848
GLUL glutamate-ammonia ligase -2.26273
TMEM267 transmembrane protein 267 -2.25984
GPC3 glypican 3 -2.25965
ATP7B ATPase, Cu++ transporting, beta polypeptide -2.25837
EED embryonic ectoderm development -2.25794
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -2.25213
PUS1 pseudouridylate synthase 1 -2.24443
FST follistatin -2.24369
MORC4 MORC family CW-type zinc finger 4 -2.24226
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -2.23837
LAGE3 L antigen family, member 3 -2.23805
FGA fibrinogen alpha chain -2.2332
USP1 ubiquitin specific peptidase 1 -2.22283
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -2.22278
SCML2 sex comb on midleg-like 2 (Drosophila) -2.22253
WNT5A wingless-type MMTV integration site family, member 5A -2.21788
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.21224
ERLIN1 ER lipid raft associated 1 -2.21129
GLDC glycine dehydrogenase (decarboxylating) -2.20818
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.20357
SMC5 structural maintenance of chromosomes 5 -2.19948
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.19931
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.19686
APOC3 apolipoprotein C-III -2.1925
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) -2.19105
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -2.17648
SESN1 sestrin 1 -2.17619
INTS3 integrator complex subunit 3 -2.16377
PGRMC1 progesterone receptor membrane component 1 -2.16183
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.15894
KIF14 kinesin family member 14 -2.1579
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.15611
FAM20B family with sequence similarity 20, member B -2.14401
TUBD1 tubulin, delta 1 -2.14388
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.14313
FBP1 fructose-1,6-bisphosphatase 1 -2.13286
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.12936
CAAP1 caspase activity and apoptosis inhibitor 1 -2.11965
NUP88 nucleoporin 88kDa -2.11849
COPZ1 coatomer protein complex, subunit zeta 1 -2.11614
LYRM1 LYR motif containing 1 -2.0978
OXA1L oxidase (cytochrome c) assembly 1-like -2.09517
TMEM33 transmembrane protein 33 -2.08963
HPX hemopexin -2.08857
ECH1 enoyl CoA hydratase 1, peroxisomal -2.08076
VAV3 vav 3 guanine nucleotide exchange factor -2.07449
HAT1 histone acetyltransferase 1 -2.06722
PDLIM1 PDZ and LIM domain 1 -2.06565
ZNF200 zinc finger protein 200 -2.06444
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.06134
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -2.06022
DENND2D DENN/MADD domain containing 2D -2.05929
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.0536
TGDS TDP-glucose 4,6-dehydratase -2.04717
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.02416
CRTAP cartilage associated protein -2.02059
CYB5A cytochrome b5 type A (microsomal) -2.01687
ELP5 elongator acetyltransferase complex subunit 5 -2.01072
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -2.01063
SAA4 serum amyloid A4, constitutive -2.01012
MYO10 myosin X -2.00247