CRCGN012_HEPG2_24H:M17 Gene Set
Genes
39 genes differentially expressed following the CRCGN012_HEPG2_24H:M17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
6.576
|
|
EAPP
|
E2F-associated phosphoprotein
|
4.48783
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.4519
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
4.34161
|
|
CSK
|
c-src tyrosine kinase
|
4.10257
|
|
RAB21
|
RAB21, member RAS oncogene family
|
3.02765
|
|
NOTCH1
|
notch 1
|
2.80678
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
2.69431
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.64296
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.62031
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.61902
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.55811
|
|
STIMATE
|
STIM activating enhancer
|
2.51646
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.47882
|
|
RALGDS
|
ral guanine nucleotide dissociation stimulator
|
2.34665
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.22667
|
|
CTSL
|
cathepsin L
|
2.15976
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.12782
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.08801
|
|
ABHD4
|
abhydrolase domain containing 4
|
2.02174
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.25751
|
|
EGF
|
epidermal growth factor
|
-4.23794
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-3.63204
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.57771
|
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-3.37583
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.27181
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-3.19481
|
|
MAP7
|
microtubule-associated protein 7
|
-3.14303
|
|
RGS2
|
regulator of G-protein signaling 2
|
-3.09348
|
|
ELAC2
|
elaC ribonuclease Z 2
|
-2.98695
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-2.87273
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-2.48598
|
|
TSPAN4
|
tetraspanin 4
|
-2.41603
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.38246
|
|
NUP62
|
nucleoporin 62kDa
|
-2.32308
|
|
HMG20B
|
high mobility group 20B
|
-2.28938
|
|
CCNB2
|
cyclin B2
|
-2.23739
|
|
CLTB
|
clathrin, light chain B
|
-2.13393
|
|
ZW10
|
zw10 kinetochore protein
|
-2.10854
|
