CRCGN012_HEPG2_24H:M20 Gene Set
Genes
50 genes differentially expressed following the CRCGN012_HEPG2_24H:M20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.21534
|
|
CSK
|
c-src tyrosine kinase
|
6.01148
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.46172
|
|
LCN2
|
lipocalin 2
|
4.12633
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.59577
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.51466
|
|
UBQLN2
|
ubiquilin 2
|
3.45036
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
3.26648
|
|
TBP
|
TATA box binding protein
|
3.1488
|
|
EPHB2
|
EPH receptor B2
|
2.92489
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.91713
|
|
INTS3
|
integrator complex subunit 3
|
2.8925
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.87768
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.83847
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.73738
|
|
SATB1
|
SATB homeobox 1
|
2.72754
|
|
MYLK
|
myosin light chain kinase
|
2.68551
|
|
NMU
|
neuromedin U
|
2.58202
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.31285
|
|
TEX10
|
testis expressed 10
|
2.25449
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.25148
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.21634
|
|
CYCS
|
cytochrome c, somatic
|
2.17367
|
|
CHN1
|
chimerin 1
|
2.13776
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.1235
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.12338
|
|
SHC1
|
SHC (Src homology 2 domain containing) transforming protein 1
|
2.082
|
|
MEST
|
mesoderm specific transcript
|
2.069
|
|
CBR3
|
carbonyl reductase 3
|
2.03049
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-6.72793
|
|
CCNB2
|
cyclin B2
|
-5.91265
|
|
DNM1L
|
dynamin 1-like
|
-4.44196
|
|
CDC20
|
cell division cycle 20
|
-4.11002
|
|
LDHD
|
lactate dehydrogenase D
|
-3.8592
|
|
GOLT1B
|
golgi transport 1B
|
-3.81052
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.78584
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.53001
|
|
PEG10
|
paternally expressed 10
|
-3.44571
|
|
EGF
|
epidermal growth factor
|
-3.35955
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.35566
|
|
CCNB1
|
cyclin B1
|
-2.96833
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.92743
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.91088
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.64513
|
|
TUBB6
|
tubulin, beta 6 class V
|
-2.56991
|
|
CD320
|
CD320 molecule
|
-2.35551
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.15276
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.10417
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.04683
|
|
AKAP8
|
A kinase (PRKA) anchor protein 8
|
-2.0351
|
