| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | pregnenolone 5.31 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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69 genes differentially expressed following the CRCGN012_HEPG2_24H:M21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 9.4041 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.42894 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 5.11903 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.95116 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.90942 |
| UBQLN2 | ubiquilin 2 | 4.90571 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.89477 |
| NOTCH1 | notch 1 | 4.79027 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.75523 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.73498 |
| PRR15L | proline rich 15-like | 4.68886 |
| TATDN2 | TatD DNase domain containing 2 | 4.50386 |
| MYLK | myosin light chain kinase | 4.13939 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.98529 |
| CHN1 | chimerin 1 | 3.94967 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 3.80702 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 3.5965 |
| ABHD6 | abhydrolase domain containing 6 | 3.42612 |
| H2BC12 | H2B clustered histone 12 | 3.27203 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.22523 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.0561 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.96284 |
| FZD1 | frizzled class receptor 1 | 2.8466 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.5413 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.50217 |
| TPD52L2 | tumor protein D52-like 2 | 2.47362 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.35523 |
| CCNA1 | cyclin A1 | 2.33649 |
| STXBP2 | syntaxin binding protein 2 | 2.22792 |
| CHD8 | chromodomain helicase DNA binding protein 8 | 2.20975 |
| LOC122526780 | uncharacterized LOC122526780 | 2.118 |
| MRPS31 | mitochondrial ribosomal protein S31 | 2.09608 |
| JADE2 | jade family PHD finger 2 | 2.09108 |
| VRK2 | vaccinia related kinase 2 | 2.09074 |
| MPHOSPH6 | M-phase phosphoprotein 6 | 2.02036 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -6.36468 |
| ADI1 | acireductone dioxygenase 1 | -5.63348 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.11364 |
| LDHD | lactate dehydrogenase D | -4.80662 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.67001 |
| TUBB6 | tubulin, beta 6 class V | -4.57305 |
| ZNF586 | zinc finger protein 586 | -4.52409 |
| CDC25B | cell division cycle 25B | -4.28827 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.17594 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.76136 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -3.72253 |
| CAB39 | calcium binding protein 39 | -3.49641 |
| SNX11 | sorting nexin 11 | -3.2202 |
| WASHC4 | WASH complex subunit 4 | -2.89567 |
| EGF | epidermal growth factor | -2.83617 |
| CCNB2 | cyclin B2 | -2.78552 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.74728 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.64283 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.61519 |
| RGS2 | regulator of G-protein signaling 2 | -2.46823 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -2.36768 |
| SOAT2 | sterol O-acyltransferase 2 | -2.27256 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -2.26841 |
| FSTL1 | follistatin-like 1 | -2.24829 |
| TRH | thyrotropin-releasing hormone | -2.16933 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -2.15309 |
| EPCIP | exosomal polycystin 1 interacting protein | -2.11961 |
| CA3 | carbonic anhydrase III | -2.11932 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -2.10572 |
| ZNF551 | zinc finger protein 551 | -2.09835 |
| AQP2 | aquaporin 2 (collecting duct) | -2.08465 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -2.06652 |
| PALMD | palmdelphin | -2.03814 |
| ZNF587B | zinc finger protein 587B | -2.00909 |
