CRCGN012_HEPG2_24H:M22 Gene Set
Genes
41 genes differentially expressed following the CRCGN012_HEPG2_24H:M22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
7.3665
|
|
E2F2
|
E2F transcription factor 2
|
4.81255
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.49354
|
|
SLC75A1
|
solute carrier family 75 member 1
|
4.28296
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
4.0412
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.74552
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.8874
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.7409
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.48511
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
2.46647
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.45251
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.44359
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.42285
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.41756
|
|
CSK
|
c-src tyrosine kinase
|
2.41712
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.38058
|
|
WDR7
|
WD repeat domain 7
|
2.22459
|
|
CEP57
|
centrosomal protein 57kDa
|
2.12303
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.04481
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
2.02651
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-6.31364
|
|
CD320
|
CD320 molecule
|
-5.21719
|
|
MAP7
|
microtubule-associated protein 7
|
-4.05444
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.86029
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.70609
|
|
RHEB
|
Ras homolog enriched in brain
|
-3.32315
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-3.30162
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.21641
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.15711
|
|
DNM1L
|
dynamin 1-like
|
-2.95762
|
|
LDHD
|
lactate dehydrogenase D
|
-2.74944
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.73319
|
|
HMG20B
|
high mobility group 20B
|
-2.72976
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.67442
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.52791
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
-2.48892
|
|
EGF
|
epidermal growth factor
|
-2.40959
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.288
|
|
WASHC4
|
WASH complex subunit 4
|
-2.28534
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.18916
|
|
PUF60
|
poly-U binding splicing factor 60KDa
|
-2.13744
|
