CRCGN012_HEPG2_24H:M23 Gene Set
Genes
48 genes differentially expressed following the CRCGN012_HEPG2_24H:M23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
7.25783
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
5.41719
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
5.36837
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.76973
|
|
SQOR
|
sulfide quinone oxidoreductase
|
4.6704
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.65464
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
4.47824
|
|
CCNF
|
cyclin F
|
4.30649
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.09858
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.2668
|
|
LAGE3
|
L antigen family, member 3
|
3.20333
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.18113
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.9528
|
|
GPATCH8
|
G patch domain containing 8
|
2.8301
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.81602
|
|
FGF21
|
fibroblast growth factor 21
|
2.47168
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.45974
|
|
CEP57
|
centrosomal protein 57kDa
|
2.35979
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.29495
|
|
LCN2
|
lipocalin 2
|
2.28468
|
|
PRR15L
|
proline rich 15-like
|
2.22567
|
|
CSK
|
c-src tyrosine kinase
|
2.21486
|
|
E2F8
|
E2F transcription factor 8
|
2.0985
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.08155
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-7.55641
|
|
CCNB1
|
cyclin B1
|
-6.55089
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.7021
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-5.18878
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-4.70281
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.65996
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.62188
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.38737
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.21711
|
|
GNAS
|
GNAS complex locus
|
-3.70537
|
|
LDHD
|
lactate dehydrogenase D
|
-2.96749
|
|
TCTN1
|
tectonic family member 1
|
-2.7771
|
|
PEG10
|
paternally expressed 10
|
-2.76475
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.62109
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.61422
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.50465
|
|
RNF167
|
ring finger protein 167
|
-2.36335
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.29861
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-2.28273
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-2.2336
|
|
CAB39
|
calcium binding protein 39
|
-2.22517
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.1804
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.04237
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.01479
|
