CRCGN012_HEPG2_24H:N01 Gene Set
Genes
35 genes differentially expressed following the CRCGN012_HEPG2_24H:N01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CSK
|
c-src tyrosine kinase
|
7.40218
|
|
CHN1
|
chimerin 1
|
4.61565
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.56653
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
4.24931
|
|
NOTCH1
|
notch 1
|
4.04311
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.89846
|
|
STAP2
|
signal transducing adaptor family member 2
|
3.73734
|
|
CBR3
|
carbonyl reductase 3
|
3.26243
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.8163
|
|
CCNF
|
cyclin F
|
2.35667
|
|
RNPS1
|
RNA binding protein S1, serine-rich domain
|
2.32647
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.32416
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.31526
|
|
GPATCH8
|
G patch domain containing 8
|
2.21056
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.16951
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.09425
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.09178
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.03394
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-4.92588
|
|
ZNF586
|
zinc finger protein 586
|
-4.55452
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.19734
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.42397
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.28093
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.01764
|
|
LSM6
|
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.95145
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-2.77524
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.62559
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.4991
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.4759
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.44691
|
|
SNX11
|
sorting nexin 11
|
-2.37893
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.31272
|
|
EGF
|
epidermal growth factor
|
-2.19764
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.13035
|
|
CAB39
|
calcium binding protein 39
|
-2.06
|
