CRCGN012_HEPG2_24H:N06 Gene Set
Genes
47 genes differentially expressed following the CRCGN012_HEPG2_24H:N06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
4.40908
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.31719
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
4.28957
|
|
PRR15L
|
proline rich 15-like
|
4.28237
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.13374
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.0849
|
|
E2F2
|
E2F transcription factor 2
|
4.08223
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.06354
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.37644
|
|
PFKL
|
phosphofructokinase, liver
|
3.31537
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
2.9987
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.99775
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.88154
|
|
CSK
|
c-src tyrosine kinase
|
2.83121
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.57616
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.51154
|
|
TLR4
|
toll-like receptor 4
|
2.49753
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.44851
|
|
TBP
|
TATA box binding protein
|
2.43353
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.35689
|
|
VGLL4
|
vestigial-like family member 4
|
2.32246
|
|
KLHL9
|
kelch-like family member 9
|
2.28045
|
|
CX3CR1
|
chemokine (C-X3-C motif) receptor 1
|
2.18097
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.1778
|
|
ZNF589
|
zinc finger protein 589
|
2.06956
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-6.3799
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.30567
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.02327
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.85175
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-3.73588
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.67361
|
|
THAP11
|
THAP domain containing 11
|
-3.51997
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.35766
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.33331
|
|
TUBB6
|
tubulin, beta 6 class V
|
-2.94758
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.80317
|
|
CDC20
|
cell division cycle 20
|
-2.78333
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.73727
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.65385
|
|
VAT1
|
vesicle amine transport 1
|
-2.6216
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.54474
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.28245
|
|
EGF
|
epidermal growth factor
|
-2.25311
|
|
CCNB1
|
cyclin B1
|
-2.23781
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.19885
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.16172
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
-2.08443
|
