CRCGN012_HEPG2_24H:N07 Gene Set
Genes
45 genes differentially expressed following the CRCGN012_HEPG2_24H:N07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.79632
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.71289
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.60136
|
|
LAGE3
|
L antigen family, member 3
|
4.50958
|
|
UBQLN2
|
ubiquilin 2
|
4.23257
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.0826
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.34009
|
|
TESK1
|
testis-specific kinase 1
|
3.01209
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.71163
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.64116
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.61341
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.51881
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.44918
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.39362
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.22042
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.14125
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.13939
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.08705
|
|
VGLL4
|
vestigial-like family member 4
|
2.07644
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.00328
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.44686
|
|
ADI1
|
acireductone dioxygenase 1
|
-5.19135
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.54956
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.1783
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.89282
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.6569
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.26204
|
|
EGF
|
epidermal growth factor
|
-3.17725
|
|
MAP7
|
microtubule-associated protein 7
|
-3.08751
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.04539
|
|
TCTN1
|
tectonic family member 1
|
-3.0287
|
|
WASHC4
|
WASH complex subunit 4
|
-2.7889
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.54326
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.51437
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-2.36735
|
|
CCNB2
|
cyclin B2
|
-2.35322
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.29532
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.21428
|
|
TSPAN4
|
tetraspanin 4
|
-2.20573
|
|
LDHD
|
lactate dehydrogenase D
|
-2.15972
|
|
CLTB
|
clathrin, light chain B
|
-2.11417
|
|
GDF15
|
growth differentiation factor 15
|
-2.07409
|
|
CD320
|
CD320 molecule
|
-2.05677
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.0178
|
|
SERPINB7
|
serpin peptidase inhibitor, clade B (ovalbumin), member 7
|
-2.00366
|
