CRCGN012_HEPG2_24H:N08 Gene Set
Genes
53 genes differentially expressed following the CRCGN012_HEPG2_24H:N08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.70336
|
|
CHN1
|
chimerin 1
|
5.62785
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.23656
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.08878
|
|
E2F2
|
E2F transcription factor 2
|
3.99446
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.89494
|
|
PRR15L
|
proline rich 15-like
|
3.77122
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.73673
|
|
MSRA
|
methionine sulfoxide reductase A
|
3.68979
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.48122
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.36949
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.24733
|
|
CCNA1
|
cyclin A1
|
3.01537
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.88128
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.82164
|
|
GNAI2
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
|
2.58194
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.37745
|
|
CYCS
|
cytochrome c, somatic
|
2.3309
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.31134
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.2578
|
|
USP6NL
|
USP6 N-terminal like
|
2.23106
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.21339
|
|
PCNA
|
proliferating cell nuclear antigen
|
2.19089
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.1103
|
|
PIGB
|
phosphatidylinositol glycan anchor biosynthesis, class B
|
2.07481
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.05623
|
|
IFI44L
|
interferon-induced protein 44-like
|
2.04443
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-6.4043
|
|
MAP7
|
microtubule-associated protein 7
|
-4.94169
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.22492
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.1228
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-4.03099
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-4.01251
|
|
VAT1
|
vesicle amine transport 1
|
-3.79465
|
|
LDHD
|
lactate dehydrogenase D
|
-3.74243
|
|
ZNF586
|
zinc finger protein 586
|
-3.73653
|
|
CCNB2
|
cyclin B2
|
-3.58861
|
|
EGF
|
epidermal growth factor
|
-3.3512
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.32685
|
|
GNAS
|
GNAS complex locus
|
-3.32541
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.30838
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.87474
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.85752
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.73701
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.70124
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.54303
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.51349
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.41604
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.40461
|
|
PGAM4
|
phosphoglycerate mutase family member 4
|
-2.33659
|
|
CCNB1
|
cyclin B1
|
-2.31226
|
|
ST14
|
suppression of tumorigenicity 14 (colon carcinoma)
|
-2.04797
|
|
SPOCK1
|
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
|
-2.00092
|
