CRCGN012_HEPG2_24H:N09 Gene Set
Genes
46 genes differentially expressed following the CRCGN012_HEPG2_24H:N09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CCNA1
|
cyclin A1
|
4.92527
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.46979
|
|
UBQLN2
|
ubiquilin 2
|
4.31818
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.30703
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.15997
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
4.06935
|
|
TXNL4B
|
thioredoxin-like 4B
|
3.77436
|
|
STK10
|
serine/threonine kinase 10
|
3.69529
|
|
HOXA10
|
homeobox A10
|
3.65011
|
|
CCNF
|
cyclin F
|
3.64286
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.57126
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.46576
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.20347
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.76948
|
|
SIRT3
|
sirtuin 3
|
2.56822
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.39591
|
|
CBR3
|
carbonyl reductase 3
|
2.35595
|
|
MSRA
|
methionine sulfoxide reductase A
|
2.34752
|
|
DCAF16
|
DDB1 and CUL4 associated factor 16
|
2.27621
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.22798
|
|
TLR4
|
toll-like receptor 4
|
2.21483
|
|
MTIF2
|
mitochondrial translational initiation factor 2
|
2.19268
|
|
MACIR
|
macrophage immunometabolism regulator
|
2.15678
|
|
MAP3K1
|
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
|
2.12783
|
|
EIF2S3
|
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
|
2.10872
|
|
HOXA10-HOXA9
|
HOXA10-HOXA9 readthrough
|
2.00834
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-7.13174
|
|
VAT1
|
vesicle amine transport 1
|
-7.128
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-5.37954
|
|
MTA1
|
metastasis associated 1
|
-3.74097
|
|
EGF
|
epidermal growth factor
|
-3.28598
|
|
THAP11
|
THAP domain containing 11
|
-2.88007
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.76423
|
|
LDHD
|
lactate dehydrogenase D
|
-2.66749
|
|
MAP7
|
microtubule-associated protein 7
|
-2.55694
|
|
TXNRD1
|
thioredoxin reductase 1
|
-2.54329
|
|
CCNB2
|
cyclin B2
|
-2.54318
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.50632
|
|
WASHC4
|
WASH complex subunit 4
|
-2.49865
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.41735
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.38796
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.30815
|
|
PPL
|
periplakin
|
-2.25924
|
|
GPRASP1
|
G protein-coupled receptor associated sorting protein 1
|
-2.24246
|
|
PLA2G4C
|
phospholipase A2, group IVC (cytosolic, calcium-independent)
|
-2.17353
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.16716
|
