CRCGN012_HEPG2_24H:N10 Gene Set
Genes
52 genes differentially expressed following the CRCGN012_HEPG2_24H:N10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CSK
|
c-src tyrosine kinase
|
4.75757
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
4.61587
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.60248
|
|
UBQLN2
|
ubiquilin 2
|
4.46901
|
|
RPL39L
|
ribosomal protein L39-like
|
4.4347
|
|
STAP2
|
signal transducing adaptor family member 2
|
4.38648
|
|
E2F2
|
E2F transcription factor 2
|
4.36408
|
|
CCNA1
|
cyclin A1
|
4.06184
|
|
GPATCH8
|
G patch domain containing 8
|
4.05717
|
|
CCNF
|
cyclin F
|
3.85183
|
|
FZD7
|
frizzled class receptor 7
|
3.77143
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.76017
|
|
CCNH
|
cyclin H
|
3.68428
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.11112
|
|
LCN2
|
lipocalin 2
|
3.04251
|
|
KIF5C
|
kinesin family member 5C
|
2.90476
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.84391
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.7623
|
|
CYCS
|
cytochrome c, somatic
|
2.66228
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.63487
|
|
TLR4
|
toll-like receptor 4
|
2.56224
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
2.30395
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
2.24508
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.14594
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.1351
|
|
HTR1E
|
5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
|
2.0145
|
|
GATA3
|
GATA binding protein 3
|
2.01344
|
|
EPHA3
|
EPH receptor A3
|
2.00391
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
BLCAP
|
bladder cancer associated protein
|
-4.83768
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-4.70541
|
|
ZNF586
|
zinc finger protein 586
|
-4.69531
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.62372
|
|
CCNB2
|
cyclin B2
|
-4.49643
|
|
PEG10
|
paternally expressed 10
|
-4.00578
|
|
GNAS
|
GNAS complex locus
|
-3.58681
|
|
GDF15
|
growth differentiation factor 15
|
-3.4779
|
|
EGF
|
epidermal growth factor
|
-3.10909
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.01503
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.01236
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.88693
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.83604
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.80579
|
|
CDC20
|
cell division cycle 20
|
-2.50651
|
|
DSG2
|
desmoglein 2
|
-2.45932
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.42531
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.28412
|
|
ZNF8
|
zinc finger protein 8
|
-2.26168
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.20809
|
|
ZNF304
|
zinc finger protein 304
|
-2.14032
|
|
ACOT2
|
acyl-CoA thioesterase 2
|
-2.11971
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.10689
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.05422
|
