CRCGN012_HEPG2_24H:N11 Gene Set
Genes
49 genes differentially expressed following the CRCGN012_HEPG2_24H:N11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INTS3
|
integrator complex subunit 3
|
5.22715
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
5.07432
|
|
PRR15L
|
proline rich 15-like
|
5.00353
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.42466
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
3.68091
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.58716
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.07121
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.02956
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.99478
|
|
CSK
|
c-src tyrosine kinase
|
2.93046
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.90492
|
|
STK10
|
serine/threonine kinase 10
|
2.88694
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.79606
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.78986
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.55537
|
|
UBQLN2
|
ubiquilin 2
|
2.524
|
|
HOOK2
|
hook microtubule-tethering protein 2
|
2.45802
|
|
ZNF589
|
zinc finger protein 589
|
2.30752
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.26729
|
|
HOXA10
|
homeobox A10
|
2.22671
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.18056
|
|
RFC5
|
replication factor C (activator 1) 5, 36.5kDa
|
2.09637
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-6.83287
|
|
ZNF586
|
zinc finger protein 586
|
-5.18575
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-5.0
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.8349
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.81231
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.60326
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.35981
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.22306
|
|
RPS5
|
ribosomal protein S5
|
-3.86845
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-3.82563
|
|
CCNB2
|
cyclin B2
|
-3.5731
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
-3.53276
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.08648
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.04394
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.95367
|
|
TXNRD1
|
thioredoxin reductase 1
|
-2.79147
|
|
DSG2
|
desmoglein 2
|
-2.68238
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.61331
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.2735
|
|
GNAS
|
GNAS complex locus
|
-2.17935
|
|
PAEP
|
progestagen-associated endometrial protein
|
-2.15999
|
|
ZNF304
|
zinc finger protein 304
|
-2.15133
|
|
EGF
|
epidermal growth factor
|
-2.14721
|
|
NT5C2
|
5'-nucleotidase, cytosolic II
|
-2.12134
|
|
ZIM3
|
zinc finger, imprinted 3
|
-2.04314
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.04303
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.03168
|
