| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-nitrosopyrrolidine 1.3 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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72 genes differentially expressed following the CRCGN012_HEPG2_24H:N12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6.63685 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 6.35678 |
| CSK | c-src tyrosine kinase | 6.17702 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.3565 |
| ATP11B | ATPase, class VI, type 11B | 4.45832 |
| MAMLD1 | mastermind-like domain containing 1 | 3.92659 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 3.85033 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 3.8356 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.74649 |
| NOTCH1 | notch 1 | 3.60094 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 3.57809 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.48258 |
| MYLK | myosin light chain kinase | 3.47474 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 3.46819 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.46278 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.44392 |
| RPL39L | ribosomal protein L39-like | 3.4094 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.17713 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.13774 |
| PRR15L | proline rich 15-like | 3.1143 |
| STIMATE | STIM activating enhancer | 3.0676 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 3.02037 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.99433 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.91998 |
| KIFBP | kinesin family binding protein | 2.87027 |
| CBR3 | carbonyl reductase 3 | 2.75815 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 2.7298 |
| HEBP1 | heme binding protein 1 | 2.54577 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.53381 |
| CHN1 | chimerin 1 | 2.5314 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 2.49842 |
| OAZ2 | ornithine decarboxylase antizyme 2 | 2.34261 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.29268 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.18892 |
| TCTA | T-cell leukemia translocation altered | 2.12221 |
| RRAGA | Ras-related GTP binding A | 2.12168 |
| ICE2 | interactor of little elongation complex ELL subunit 2 | 2.07839 |
| MAP7 | microtubule-associated protein 7 | 2.01209 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNM1L | dynamin 1-like | -6.44825 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.24859 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -4.62093 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.84653 |
| CCDC86 | coiled-coil domain containing 86 | -3.74043 |
| VAT1 | vesicle amine transport 1 | -3.7097 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.685 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.64223 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.55836 |
| NUP85 | nucleoporin 85kDa | -3.42283 |
| RGS2 | regulator of G-protein signaling 2 | -3.34098 |
| PGAM4 | phosphoglycerate mutase family member 4 | -3.3121 |
| CD320 | CD320 molecule | -3.24146 |
| GDF15 | growth differentiation factor 15 | -3.22833 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -3.22833 |
| LDHD | lactate dehydrogenase D | -3.19619 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -3.16103 |
| ADI1 | acireductone dioxygenase 1 | -3.15897 |
| CHMP4B | charged multivesicular body protein 4B | -3.03032 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.81734 |
| GTPBP8 | GTP-binding protein 8 (putative) | -2.69035 |
| TLCD3A | TLC domain containing 3A | -2.60618 |
| CDC20 | cell division cycle 20 | -2.52624 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.45698 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.35386 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.33579 |
| EGF | epidermal growth factor | -2.32633 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.31065 |
| PCNA | proliferating cell nuclear antigen | -2.30899 |
| MRPS7 | mitochondrial ribosomal protein S7 | -2.23903 |
| RPS5 | ribosomal protein S5 | -2.22436 |
| ZW10 | zw10 kinetochore protein | -2.20179 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.11188 |
| TWF2 | twinfilin actin binding protein 2 | -2.06692 |
