CRCGN012_HEPG2_24H:N14 Gene Set
Genes
34 genes differentially expressed following the CRCGN012_HEPG2_24H:N14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MSRA
|
methionine sulfoxide reductase A
|
4.40012
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.38507
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.08324
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.74436
|
|
ZFP36
|
ZFP36 ring finger protein
|
3.31762
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
3.24126
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.17739
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.11766
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.98343
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.69248
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.64375
|
|
CHEK2
|
checkpoint kinase 2
|
2.62368
|
|
PSMB10
|
proteasome (prosome, macropain) subunit, beta type, 10
|
2.44762
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
2.13384
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.0742
|
|
SERPINE2
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
|
2.02267
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-7.23318
|
|
LDHD
|
lactate dehydrogenase D
|
-4.95174
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.81124
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-4.47697
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.45251
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.34925
|
|
TSPAN4
|
tetraspanin 4
|
-4.05081
|
|
MAP7
|
microtubule-associated protein 7
|
-3.91561
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-3.74568
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.69848
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.6568
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.23472
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.51102
|
|
EGF
|
epidermal growth factor
|
-2.3729
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.36462
|
|
PDLIM1
|
PDZ and LIM domain 1
|
-2.27329
|
|
HMG20B
|
high mobility group 20B
|
-2.09433
|
|
REPS2
|
RALBP1 associated Eps domain containing 2
|
-2.07844
|
