CRCGN012_HEPG2_24H:N15 Gene Set
Genes
50 genes differentially expressed following the CRCGN012_HEPG2_24H:N15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
JADE2
|
jade family PHD finger 2
|
5.5152
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.49462
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.2423
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
5.04983
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.04425
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.92564
|
|
UBQLN2
|
ubiquilin 2
|
4.79329
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
4.6672
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.52431
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
4.13701
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.94903
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.25474
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
3.15351
|
|
EVL
|
Enah/Vasp-like
|
3.00277
|
|
CYCS
|
cytochrome c, somatic
|
2.97038
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.82679
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.63167
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.56265
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.47411
|
|
ZNF589
|
zinc finger protein 589
|
2.41192
|
|
EPHA3
|
EPH receptor A3
|
2.3303
|
|
SLC75A1
|
solute carrier family 75 member 1
|
2.24348
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.22993
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
2.20125
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.07152
|
|
UBXN2B
|
UBX domain protein 2B
|
2.0166
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-4.93477
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-4.91233
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.81181
|
|
LDHD
|
lactate dehydrogenase D
|
-4.30511
|
|
EGF
|
epidermal growth factor
|
-4.23211
|
|
MAP7
|
microtubule-associated protein 7
|
-4.04198
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.70199
|
|
WASHC4
|
WASH complex subunit 4
|
-3.6233
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.54131
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.45301
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.17369
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.96306
|
|
ATG2A
|
autophagy related 2A
|
-2.941
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.85739
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.76031
|
|
SESN1
|
sestrin 1
|
-2.55697
|
|
SPAG4
|
sperm associated antigen 4
|
-2.49036
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
-2.45696
|
|
ZFTA
|
zinc finger translocation associated
|
-2.34025
|
|
TSPAN3
|
tetraspanin 3
|
-2.32988
|
|
PILRB
|
paired immunoglobin-like type 2 receptor beta
|
-2.29924
|
|
PREB
|
prolactin regulatory element binding
|
-2.12104
|
|
REEP5
|
receptor accessory protein 5
|
-2.07397
|
|
PLXNB2
|
plexin B2
|
-2.06402
|
