CRCGN012_HEPG2_24H:N16 Gene Set
Genes
48 genes differentially expressed following the CRCGN012_HEPG2_24H:N16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
9.13422
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
5.16394
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.99155
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.81897
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.79527
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.64814
|
|
MEST
|
mesoderm specific transcript
|
4.62271
|
|
RAB21
|
RAB21, member RAS oncogene family
|
4.52362
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.45248
|
|
E2F2
|
E2F transcription factor 2
|
4.39681
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.26039
|
|
CSK
|
c-src tyrosine kinase
|
4.24537
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.65208
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.56313
|
|
PRKCH
|
protein kinase C, eta
|
3.09491
|
|
JADE2
|
jade family PHD finger 2
|
3.04952
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.75349
|
|
CCNF
|
cyclin F
|
2.73656
|
|
STIMATE
|
STIM activating enhancer
|
2.72839
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.65519
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.59262
|
|
KIF20A
|
kinesin family member 20A
|
2.24166
|
|
MX1
|
MX dynamin-like GTPase 1
|
2.24023
|
|
IFIT1
|
interferon-induced protein with tetratricopeptide repeats 1
|
2.09054
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.08963
|
|
MRPL46
|
mitochondrial ribosomal protein L46
|
2.07649
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLCD3A
|
TLC domain containing 3A
|
-5.51408
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.84151
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.64227
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.23319
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.11234
|
|
GNAS
|
GNAS complex locus
|
-3.53005
|
|
EGF
|
epidermal growth factor
|
-3.46583
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.40345
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
-3.32226
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.66557
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.61218
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.60627
|
|
RPS5
|
ribosomal protein S5
|
-2.59045
|
|
USP6NL
|
USP6 N-terminal like
|
-2.56074
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.37354
|
|
NR0B2
|
nuclear receptor subfamily 0, group B, member 2
|
-2.33088
|
|
LGMN
|
legumain
|
-2.27038
|
|
KIT
|
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
|
-2.2273
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
-2.21914
|
|
TATDN2
|
TatD DNase domain containing 2
|
-2.08626
|
|
SQSTM1
|
sequestosome 1
|
-2.07824
|
|
USP1
|
ubiquitin specific peptidase 1
|
-2.05365
|
