CRCGN012_HEPG2_24H:N17 Gene Set
Genes
41 genes differentially expressed following the CRCGN012_HEPG2_24H:N17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CYCS
|
cytochrome c, somatic
|
6.0091
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.91348
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.47895
|
|
CHN1
|
chimerin 1
|
4.38266
|
|
CBR3
|
carbonyl reductase 3
|
4.24771
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.0529
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.89632
|
|
EPN2
|
epsin 2
|
3.59796
|
|
TCEAL4
|
transcription elongation factor A (SII)-like 4
|
3.23961
|
|
PRR15L
|
proline rich 15-like
|
2.33513
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.29314
|
|
CA3
|
carbonic anhydrase III
|
2.25387
|
|
HAPSTR1
|
HUWE1 associated protein modifying stress responses
|
2.23949
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.15217
|
|
NDUFA13
|
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
|
2.14131
|
|
SLC4A8
|
solute carrier family 4, sodium bicarbonate cotransporter, member 8
|
2.09614
|
|
CDH10
|
cadherin 10, type 2 (T2-cadherin)
|
2.04843
|
|
TFEC
|
transcription factor EC
|
2.02793
|
|
ACE2
|
angiotensin I converting enzyme 2
|
2.02519
|
|
SNX7
|
sorting nexin 7
|
2.02351
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-9.79425
|
|
CDC20
|
cell division cycle 20
|
-5.07398
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.77312
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.59445
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-4.5516
|
|
LDHD
|
lactate dehydrogenase D
|
-4.3896
|
|
THAP11
|
THAP domain containing 11
|
-4.36667
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.13152
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.10265
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-3.74399
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.41703
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.37432
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.10415
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.4728
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
-2.40514
|
|
TRAPPC6A
|
trafficking protein particle complex 6A
|
-2.40469
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.2758
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.18958
|
|
HOXA3
|
homeobox A3
|
-2.08696
|
|
GORASP1
|
golgi reassembly stacking protein 1, 65kDa
|
-2.07787
|
|
YIPF1
|
Yip1 domain family, member 1
|
-2.00522
|
