| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | aroclor 1016 1.21 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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51 genes differentially expressed following the CRCGN012_HEPG2_24H:N18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 8.27648 |
| PRR15L | proline rich 15-like | 5.77924 |
| E2F2 | E2F transcription factor 2 | 5.2945 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 4.99003 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.87916 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.68659 |
| HOXA10 | homeobox A10 | 4.23582 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.10287 |
| NOSIP | nitric oxide synthase interacting protein | 3.55867 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.05723 |
| NOTCH1 | notch 1 | 2.90445 |
| CYCS | cytochrome c, somatic | 2.86473 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.73117 |
| UBQLN2 | ubiquilin 2 | 2.72726 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.62251 |
| COPS7A | COP9 signalosome subunit 7A | 2.37338 |
| ICAM1 | intercellular adhesion molecule 1 | 2.293 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 | 2.29173 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.27438 |
| XPO4 | exportin 4 | 2.21174 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 2.13058 |
| CEP57 | centrosomal protein 57kDa | 2.12199 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.10403 |
| PRPF39 | pre-mRNA processing factor 39 | 2.03578 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.00962 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.00754 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADI1 | acireductone dioxygenase 1 | -9.09708 |
| CCNB2 | cyclin B2 | -7.4923 |
| MRPS2 | mitochondrial ribosomal protein S2 | -6.82517 |
| TLCD3A | TLC domain containing 3A | -5.78938 |
| GNAS | GNAS complex locus | -5.74784 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -5.40064 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.98855 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.70041 |
| VDAC1 | voltage-dependent anion channel 1 | -4.23406 |
| MAP7 | microtubule-associated protein 7 | -4.15474 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.2702 |
| CDC25B | cell division cycle 25B | -3.13527 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.08276 |
| GDF15 | growth differentiation factor 15 | -2.87148 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.8694 |
| RBM15B | RNA binding motif protein 15B | -2.40157 |
| NLRP4 | NLR family, pyrin domain containing 4 | -2.39139 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.30967 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -2.30437 |
| CAB39 | calcium binding protein 39 | -2.25644 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.20938 |
| RGS2 | regulator of G-protein signaling 2 | -2.1922 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.18705 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -2.17919 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.04242 |
