CRCGN012_HEPG2_24H:N21 Gene Set
Genes
44 genes differentially expressed following the CRCGN012_HEPG2_24H:N21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
8.81327
|
|
UBQLN2
|
ubiquilin 2
|
5.82838
|
|
CYCS
|
cytochrome c, somatic
|
5.66574
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.65589
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.5199
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.47396
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.33886
|
|
PLSCR1
|
phospholipid scramblase 1
|
4.2896
|
|
CSK
|
c-src tyrosine kinase
|
4.24207
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.80026
|
|
CBR3
|
carbonyl reductase 3
|
3.68574
|
|
KLHL21
|
kelch-like family member 21
|
3.46296
|
|
PRKCH
|
protein kinase C, eta
|
2.85417
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.81411
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.56893
|
|
HEBP1
|
heme binding protein 1
|
2.46785
|
|
NDUFAF4
|
NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
|
2.35215
|
|
SGCB
|
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
|
2.33374
|
|
MAP7
|
microtubule-associated protein 7
|
2.29044
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
2.13115
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
2.09304
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GNAS
|
GNAS complex locus
|
-6.87261
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.21527
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.12799
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.98867
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.96061
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.68428
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.3671
|
|
USP6NL
|
USP6 N-terminal like
|
-2.8351
|
|
EGF
|
epidermal growth factor
|
-2.81478
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.67504
|
|
NVL
|
nuclear VCP-like
|
-2.50044
|
|
CCNB2
|
cyclin B2
|
-2.4418
|
|
G6PC1
|
glucose-6-phosphatase catalytic subunit 1
|
-2.35019
|
|
RCVRN
|
recoverin
|
-2.33254
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
-2.26975
|
|
CAB39
|
calcium binding protein 39
|
-2.24953
|
|
PSMB10
|
proteasome (prosome, macropain) subunit, beta type, 10
|
-2.2078
|
|
CA5A
|
carbonic anhydrase VA, mitochondrial
|
-2.1936
|
|
BEND5
|
BEN domain containing 5
|
-2.1548
|
|
RTN1
|
reticulon 1
|
-2.14836
|
|
NPPA
|
natriuretic peptide A
|
-2.06758
|
|
GIT1
|
G protein-coupled receptor kinase interacting ArfGAP 1
|
-2.06261
|
|
LMO1
|
LIM domain only 1 (rhombotin 1)
|
-2.00337
|
