CRCGN012_HEPG2_24H:N22 Gene Set
Genes
39 genes differentially expressed following the CRCGN012_HEPG2_24H:N22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CSK
|
c-src tyrosine kinase
|
6.58084
|
|
E2F2
|
E2F transcription factor 2
|
6.02683
|
|
GPATCH8
|
G patch domain containing 8
|
5.84904
|
|
RAB21
|
RAB21, member RAS oncogene family
|
5.49751
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.44181
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
3.61975
|
|
STAP2
|
signal transducing adaptor family member 2
|
3.58059
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.49995
|
|
PRR15L
|
proline rich 15-like
|
3.48254
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.47948
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.41353
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.38106
|
|
NOTCH1
|
notch 1
|
3.23268
|
|
MYLK
|
myosin light chain kinase
|
3.03486
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.83919
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.81968
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.55041
|
|
UBQLN2
|
ubiquilin 2
|
2.54249
|
|
CHN1
|
chimerin 1
|
2.43847
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.36792
|
|
MMP1
|
matrix metallopeptidase 1
|
2.36565
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.2926
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.11515
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-4.3292
|
|
MAP7
|
microtubule-associated protein 7
|
-4.21614
|
|
TMEM109
|
transmembrane protein 109
|
-3.66099
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.59978
|
|
EGF
|
epidermal growth factor
|
-3.57682
|
|
THAP11
|
THAP domain containing 11
|
-3.26195
|
|
CCNB2
|
cyclin B2
|
-3.21824
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.08787
|
|
LDHD
|
lactate dehydrogenase D
|
-3.04484
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.92578
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.90828
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.80558
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.47226
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.13662
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.04599
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.03
|
