CRCGN012_HEPG2_24H:N23 Gene Set
Genes
31 genes differentially expressed following the CRCGN012_HEPG2_24H:N23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ADRB2
|
adrenoceptor beta 2, surface
|
8.37288
|
|
CCNF
|
cyclin F
|
5.52807
|
|
LCN2
|
lipocalin 2
|
5.41842
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.8238
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.58269
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.32134
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.18636
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.15179
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.0395
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.83046
|
|
MOK
|
MOK protein kinase
|
3.82569
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.80866
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.76164
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.73286
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.60507
|
|
HOXA10
|
homeobox A10
|
3.39458
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
3.28144
|
|
EPHA3
|
EPH receptor A3
|
2.92236
|
|
PRR15L
|
proline rich 15-like
|
2.49698
|
|
ZNF589
|
zinc finger protein 589
|
2.44582
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.33742
|
|
JADE2
|
jade family PHD finger 2
|
2.18006
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.09011
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.05163
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.28027
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.17469
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.13106
|
|
ELAC2
|
elaC ribonuclease Z 2
|
-3.4342
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-3.27196
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.19267
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.2655
|
