CRCGN012_HEPG2_24H:N24 Gene Set
Genes
42 genes differentially expressed following the CRCGN012_HEPG2_24H:N24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.56465
|
|
NOTCH1
|
notch 1
|
5.11162
|
|
CSK
|
c-src tyrosine kinase
|
5.04704
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.51307
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.40706
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.03515
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.58938
|
|
STK10
|
serine/threonine kinase 10
|
3.25995
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.18841
|
|
EPHB2
|
EPH receptor B2
|
3.1601
|
|
LCN2
|
lipocalin 2
|
3.02294
|
|
EVL
|
Enah/Vasp-like
|
2.88314
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.84389
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.84354
|
|
NMU
|
neuromedin U
|
2.81462
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.70049
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
2.5899
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
2.4944
|
|
BLMH
|
bleomycin hydrolase
|
2.35807
|
|
GPATCH8
|
G patch domain containing 8
|
2.29824
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.1996
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.16358
|
|
CBR3
|
carbonyl reductase 3
|
2.10441
|
|
TCEAL4
|
transcription elongation factor A (SII)-like 4
|
2.04629
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-7.28416
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.48749
|
|
HMG20B
|
high mobility group 20B
|
-3.97487
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.6594
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.52438
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.3121
|
|
NISCH
|
nischarin
|
-3.16773
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.9326
|
|
ZNF586
|
zinc finger protein 586
|
-2.90621
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.7156
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
-2.61764
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.55614
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.54381
|
|
CD320
|
CD320 molecule
|
-2.29958
|
|
CCNB1
|
cyclin B1
|
-2.14513
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.07933
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.03116
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.00296
|
