CRCGN012_HEPG2_24H:O07 Gene Set
Genes
49 genes differentially expressed following the CRCGN012_HEPG2_24H:O07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MCOLN1
|
mucolipin 1
|
6.33442
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.98172
|
|
CYCS
|
cytochrome c, somatic
|
3.84848
|
|
NOTCH1
|
notch 1
|
3.81718
|
|
PRR15L
|
proline rich 15-like
|
3.607
|
|
GPATCH8
|
G patch domain containing 8
|
3.56603
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.53496
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.28998
|
|
CSK
|
c-src tyrosine kinase
|
3.25103
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.16306
|
|
MYLK
|
myosin light chain kinase
|
3.14314
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.11173
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.05192
|
|
CCNH
|
cyclin H
|
3.00316
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.86109
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.84162
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.72513
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.69654
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.66554
|
|
CBR3
|
carbonyl reductase 3
|
2.63853
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.54531
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.47961
|
|
MAP7
|
microtubule-associated protein 7
|
2.30845
|
|
HDGFL3
|
HDGF like 3
|
2.28498
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.16212
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.01992
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-7.01925
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-6.97438
|
|
ADI1
|
acireductone dioxygenase 1
|
-6.42909
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-4.96991
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-4.05211
|
|
COG7
|
component of oligomeric golgi complex 7
|
-4.03079
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.94052
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.60753
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.53044
|
|
PEG10
|
paternally expressed 10
|
-3.46757
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.44755
|
|
ZNF586
|
zinc finger protein 586
|
-3.42476
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.31407
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.98205
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.97941
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.90953
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-2.33221
|
|
CCNB2
|
cyclin B2
|
-2.28068
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.2763
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.20308
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.17121
|
|
IFRD2
|
interferon-related developmental regulator 2
|
-2.13771
|
|
CD58
|
CD58 molecule
|
-2.07776
|
