CRCGN012_HEPG2_24H:O09 Gene Set
Genes
44 genes differentially expressed following the CRCGN012_HEPG2_24H:O09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
KLHL21
|
kelch-like family member 21
|
5.24203
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
5.15311
|
|
CHMP6
|
charged multivesicular body protein 6
|
5.01424
|
|
JADE2
|
jade family PHD finger 2
|
4.96326
|
|
PLS1
|
plastin 1
|
4.90635
|
|
CHN1
|
chimerin 1
|
4.77859
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
4.2848
|
|
STK10
|
serine/threonine kinase 10
|
4.17472
|
|
CYCS
|
cytochrome c, somatic
|
3.49169
|
|
ZNF589
|
zinc finger protein 589
|
3.3289
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.32343
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.25736
|
|
GPATCH8
|
G patch domain containing 8
|
2.88247
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.87836
|
|
HEBP1
|
heme binding protein 1
|
2.8061
|
|
MEST
|
mesoderm specific transcript
|
2.66011
|
|
IDE
|
insulin-degrading enzyme
|
2.64992
|
|
PPWD1
|
peptidylprolyl isomerase domain and WD repeat containing 1
|
2.6311
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
2.62867
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.5811
|
|
PIGB
|
phosphatidylinositol glycan anchor biosynthesis, class B
|
2.41179
|
|
CCNF
|
cyclin F
|
2.30939
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.27068
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.22799
|
|
HTRA1
|
HtrA serine peptidase 1
|
2.21367
|
|
TBP
|
TATA box binding protein
|
2.13874
|
|
TSPAN12
|
tetraspanin 12
|
2.12567
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.08321
|
|
PLP2
|
proteolipid protein 2 (colonic epithelium-enriched)
|
2.05447
|
|
BAX
|
BCL2-associated X protein
|
2.05269
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-5.00569
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.56823
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-4.45786
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.32668
|
|
LDHD
|
lactate dehydrogenase D
|
-3.91416
|
|
CCNB2
|
cyclin B2
|
-3.4498
|
|
MAP7
|
microtubule-associated protein 7
|
-3.3417
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.62603
|
|
BLCAP
|
bladder cancer associated protein
|
-2.52069
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-2.32912
|
|
REEP5
|
receptor accessory protein 5
|
-2.26742
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.26453
|
|
USP6NL
|
USP6 N-terminal like
|
-2.11162
|
|
PREB
|
prolactin regulatory element binding
|
-2.09121
|
