CRCGN012_HEPG2_24H:O10 Gene Set
Genes
50 genes differentially expressed following the CRCGN012_HEPG2_24H:O10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
7.84895
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
7.68089
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
6.24766
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
5.06928
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
5.00941
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.75952
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
4.75463
|
|
VGLL4
|
vestigial-like family member 4
|
4.507
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.40332
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.12897
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.96966
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.9572
|
|
CYCS
|
cytochrome c, somatic
|
2.93725
|
|
CSK
|
c-src tyrosine kinase
|
2.74697
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
2.55929
|
|
MYLK
|
myosin light chain kinase
|
2.46201
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.4506
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.38669
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.16948
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.1117
|
|
ANTKMT
|
adenine nucleotide translocase lysine methyltransferase
|
2.09691
|
|
MICALL1
|
MICAL-like 1
|
2.06042
|
|
TGFB3
|
transforming growth factor, beta 3
|
2.01684
|
|
UBQLN2
|
ubiquilin 2
|
2.00355
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-7.12183
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.56541
|
|
ZNF586
|
zinc finger protein 586
|
-5.05714
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.9044
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.33467
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.0607
|
|
HAT1
|
histone acetyltransferase 1
|
-2.99233
|
|
CCNB2
|
cyclin B2
|
-2.97381
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.84991
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.6697
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.53537
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-2.35256
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.29364
|
|
GNAS
|
GNAS complex locus
|
-2.2726
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.25258
|
|
POM121L2
|
POM121 transmembrane nucleoporin-like 2
|
-2.18088
|
|
HERC3
|
HECT and RLD domain containing E3 ubiquitin protein ligase 3
|
-2.15214
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.14385
|
|
UCP1
|
uncoupling protein 1 (mitochondrial, proton carrier)
|
-2.14127
|
|
SPAM1
|
sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
|
-2.03665
|
|
EGF
|
epidermal growth factor
|
-2.0303
|
|
DNM1L
|
dynamin 1-like
|
-2.0195
|
|
SPINT4
|
serine peptidase inhibitor, Kunitz type 4
|
-2.01119
|
|
ZP2
|
zona pellucida glycoprotein 2 (sperm receptor)
|
-2.0077
|
|
ZNF571
|
zinc finger protein 571
|
-2.00179
|
|
CEP41
|
centrosomal protein 41kDa
|
-2.00119
|
